ASS-Nonresponse Following Cardiac Surgery as Assessed With Multiple Electrode Aggregometry

NCT ID: NCT01824147

Last Updated: 2016-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-08-31

Study Completion Date

2015-08-31

Brief Summary

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It is the aim of the present study to assess the prevalence of ASS-Nonresponse following cardiac surgery using the Multiple Electrode Aggregometry (MEA).

Detailed Description

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Up to now there are no data concerning the prevalence of ASS-Nonresponse following surgical coronary revascularization procedures as assessed with the Multiple Electrode Aggregometry. Results of the present observational study are needed to assess the prevalence of ASS-Nonresponse in order to perform a sample size analysis for a prospective interventional study in a second step.

Conditions

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ASS-Nonresponse

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CABG Patients

Patients undergoing surgery for coronary revascularization.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients older than 18 years after cardiac surgery
* Antiaggregatory therapy with aspirin postoperatively

Exclusion Criteria

* known allergy to aspirin
* need for an antiaggregatory therapy other than aspirin
* pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Goettingen

OTHER

Sponsor Role collaborator

Goethe University

OTHER

Sponsor Role lead

Responsible Party

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Christian F. Weber, MD

Dr.med. Dr.med. habil Christian F. Weber

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christian F Weber, MD

Role: PRINCIPAL_INVESTIGATOR

Goethe University Frankfurt

Locations

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Goethe - University

Frankfurt am Main, Hesse, Germany

Site Status

University Hospital Goettingen

Göttingen, Lower Saxony, Germany

Site Status

Countries

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Germany

References

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Collet JP, Cuisset T, Range G, Cayla G, Elhadad S, Pouillot C, Henry P, Motreff P, Carrie D, Boueri Z, Belle L, Van Belle E, Rousseau H, Aubry P, Monsegu J, Sabouret P, O'Connor SA, Abtan J, Kerneis M, Saint-Etienne C, Barthelemy O, Beygui F, Silvain J, Vicaut E, Montalescot G; ARCTIC Investigators. Bedside monitoring to adjust antiplatelet therapy for coronary stenting. N Engl J Med. 2012 Nov 29;367(22):2100-9. doi: 10.1056/NEJMoa1209979. Epub 2012 Nov 4.

Reference Type BACKGROUND
PMID: 23121439 (View on PubMed)

Other Identifiers

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33/13

Identifier Type: -

Identifier Source: org_study_id

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