The Role of Serum Anticholinergic Activity in ACVB Patients

NCT ID: NCT00782938

Last Updated: 2010-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-05-31

Study Completion Date

2010-01-31

Brief Summary

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Drugs with anticholinergic potential increase the risk of postoperative transient and persistent cognitive dysfunction especially in cardiac patients. The investigators main goal is to identify preoperative risk factors and to monitor postoperative patients' state in relation to SAA activity and bilateral BIS-EEG changes.

Detailed Description

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Conditions

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Acetylcholine Cognition BIS-EEG

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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low SAA

No interventions assigned to this group

high SAA

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* written compliance to the study participation
* a good knowledge in German speech
* no red/ green blindness
* no previous neurological and/or psychiatric illness
* good ability to see and to hear
* Mini-Mental-State-Examination (MMSE) better than 25 points

Exclusion Criteria

* no written compliance to the study participation
* bad knowledge in German speech
* red/ green blindness
* previous neurological and/or psychiatric illness
* no ability to see and to hear
* Mini-Mental-State-Examination (MMSE) lower than 25 points
Minimum Eligible Age

55 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heidelberg University

OTHER

Sponsor Role lead

Responsible Party

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Department of Anesthesiology

Principal Investigators

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Eike Martin, Prof.

Role: STUDY_CHAIR

Department of Anesthesiology, University of Heidelberg

Locations

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University of Heidelberg, Department of Anesthesiology, Heidelberg Medical School

Heidelberg, Baden-Wurttemberg, Germany

Site Status

Countries

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Germany

Related Links

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Other Identifiers

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S235-2008

Identifier Type: -

Identifier Source: org_study_id

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