Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
60 participants
OBSERVATIONAL
2012-10-31
2014-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Low disinhibition
fMRI during fed and fasted states
No interventions assigned to this group
High disinhibition
fMRI during fed and fasted states
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* 21 to 45 years old
* English as first language
* Right-handed
* Have normal eyesight, or have long-sightedness or myopia within +8.0 to -8.0 diopters (unless corrected by contact lenses)
* Weigh less than 100kg with an abdominal circumference of less than 120cm
* Non-smoker, or only smoke occasionally (less than 5 sticks a week)
* Consume less than 2 units (200 mg) of caffeine a day
* Consume less than 21 units of alcohol per week (e.g. 500ml 5% beer = 2.5 units, 250ml 14% wine = 3.5 unit)
* Habitually sleep before 1am and wake before 9am
Exclusion Criteria
* History of food allergies
* History of psychiatric or neurological disorders
* History of chronic medical illness
* Metal implants in or on the body (e.g. braces, dental retainers, pacemakers)
* Shift worker
* Claustrophobic
* High astigmatism (high = \>2.00 diopters)
* Colour-blind
21 Years
45 Years
ALL
Yes
Sponsors
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Institute for Human Development and Potential (IHDP), Singapore
OTHER
Duke-NUS Graduate Medical School
OTHER
Responsible Party
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MChee
Professor
Principal Investigators
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Michael WL Chee, MBBS
Role: PRINCIPAL_INVESTIGATOR
Duke-NUS Graduate Medical School
Locations
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Centre for Cognitive Neuroscience scanner suite
Singapore, Singapore, Singapore
Countries
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References
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Plassmann H, O'Doherty J, Rangel A. Orbitofrontal cortex encodes willingness to pay in everyday economic transactions. J Neurosci. 2007 Sep 12;27(37):9984-8. doi: 10.1523/JNEUROSCI.2131-07.2007.
Knutson B, Westdorp A, Kaiser E, Hommer D. FMRI visualization of brain activity during a monetary incentive delay task. Neuroimage. 2000 Jul;12(1):20-7. doi: 10.1006/nimg.2000.0593.
Other Identifiers
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VOFIO3G
Identifier Type: -
Identifier Source: org_study_id
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