Effects of Osteopathic Treatment on Pulmonary Function After Coronary Artery Bypass Graft Surgery

NCT ID: NCT01714791

Last Updated: 2018-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2017-12-31

Brief Summary

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The purpose of this study is to determine the short and long term effects of osteopathic treatment on pulmonary function, pain and quality of life in patients after coronary artery bypass graft (CABG) surgery. The study is a randomized controlled trial.

Detailed Description

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Coronary artery bypass graft (CABG) surgery is performed worldwide. Several studies have found that there is a decrease in pulmonary function, loss of thoracic mobility and a high prevalence of chronic poststernotomy pain (CPSP) after CABG. So far there is no effective treatment for these conditions. The OstinCare study aims to investigate whether osteopathic treatment has an added value in the treatment of these patients.

Conditions

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Mechanical Complication of Coronary Artery Bypass Graft Respiratory Depression Pain Quality of Life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Usual care

Patients following the outpatient cardiac rehabilitation program.

Group Type ACTIVE_COMPARATOR

Usual care

Intervention Type OTHER

Patients exercise at a heart rate corresponding to 65% of baseline Vo2peak. Each exercise training session takes 40-60 minutes. Exercise time is apportioned as follows: 42% on the treadmill, 33% on the circle ergometer and 25% on the arm cranking device. All patients exercise under close supervision 3 days per week for a total duration of 12 weeks.

Usual care and Osteopathic treatment

Patients following the outpatient cardiac rehabilitation program and receiving osteopathic treatment.

Group Type EXPERIMENTAL

Usual care

Intervention Type OTHER

Patients exercise at a heart rate corresponding to 65% of baseline Vo2peak. Each exercise training session takes 40-60 minutes. Exercise time is apportioned as follows: 42% on the treadmill, 33% on the circle ergometer and 25% on the arm cranking device. All patients exercise under close supervision 3 days per week for a total duration of 12 weeks.

Osteopathic treatment

Intervention Type OTHER

Patients receive 4 osteopathic treatments (OT). OT is performed in week 4, 5, 8 and 12 postoperative. Depending on what is found in the patient, treatments consist mostly of one or more of the following approaches:

* Structural High Velocity Low Amplitude-techniques.
* Muscle Energy Techniques.
* General osteopathic mobilisations.
* Functional techniques (Sutherland-, Jones-techniques,…) including inhibition techniques.
* Fascia techniques.
* Soft tissue- and connective tissue techniques.
* Neurovisceral and neurolymphatic reflex techniques.
* Fluidal techniques (lymphatic manipulative techniques,...).
* Visceral manipulations.
* Neurocranial and viscerocranial techniques.

Interventions

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Usual care

Patients exercise at a heart rate corresponding to 65% of baseline Vo2peak. Each exercise training session takes 40-60 minutes. Exercise time is apportioned as follows: 42% on the treadmill, 33% on the circle ergometer and 25% on the arm cranking device. All patients exercise under close supervision 3 days per week for a total duration of 12 weeks.

Intervention Type OTHER

Osteopathic treatment

Patients receive 4 osteopathic treatments (OT). OT is performed in week 4, 5, 8 and 12 postoperative. Depending on what is found in the patient, treatments consist mostly of one or more of the following approaches:

* Structural High Velocity Low Amplitude-techniques.
* Muscle Energy Techniques.
* General osteopathic mobilisations.
* Functional techniques (Sutherland-, Jones-techniques,…) including inhibition techniques.
* Fascia techniques.
* Soft tissue- and connective tissue techniques.
* Neurovisceral and neurolymphatic reflex techniques.
* Fluidal techniques (lymphatic manipulative techniques,...).
* Visceral manipulations.
* Neurocranial and viscerocranial techniques.

Intervention Type OTHER

Other Intervention Names

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Outpatient cardiac rehabilitation

Eligibility Criteria

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Inclusion Criteria

* Planned Coronary Artery Bypass Graft (CABG) surgery at the Jessa Hospital Hasselt
* Planned Endoscopic Atraumatic Coronary Artery Bypass (endo ACAB) surgery at the Jessa Hospital
* Planned Minimal Invasive Aortic Valve Replacement (mini AVR) surgery at the Jessa Hospital

Exclusion Criteria

* Thoracic surgery in the past
* Redo CABG
* Complications after CABG, requiring long-term (more than 6 days) admission to intensive care
* Pathologies of the lungs
* Pathologies of the heart, other than the coronary artery disease
* Surgery in the sub diaphragmatic region: epigastric region, left and right hypochondriac region.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hartcentrum Hasselt

OTHER

Sponsor Role lead

Responsible Party

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Roncada Gert

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gert Roncada, DO, MSc

Role: PRINCIPAL_INVESTIGATOR

Heart Centre Hasselt

Locations

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Cardiac rehabilitation centre at the Jessa Hospital Hasselt

Hasselt, Limburg, Belgium

Site Status

Countries

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Belgium

References

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Kristjansdottir A, Ragnarsdottir M, Hannesson P, Beck HJ, Torfason B. Chest wall motion and pulmonary function are more diminished following cardiac surgery when the internal mammary artery retractor is used. Scand Cardiovasc J. 2004 Dec;38(6):369-74. doi: 10.1080/14017430410016396.

Reference Type BACKGROUND
PMID: 15804805 (View on PubMed)

Kristjansdottir A, Ragnarsdottir M, Hannesson P, Beck HJ, Torfason B. Respiratory movements are altered three months and one year following cardiac surgery. Scand Cardiovasc J. 2004 May;38(2):98-103. doi: 10.1080/14017430410028492.

Reference Type BACKGROUND
PMID: 15204235 (View on PubMed)

Ragnarsdottir M, Kristinsdottir EK. Breathing movements and breathing patterns among healthy men and women 20-69 years of age. Reference values. Respiration. 2006;73(1):48-54. doi: 10.1159/000087456. Epub 2005 Aug 11.

Reference Type BACKGROUND
PMID: 16106113 (View on PubMed)

Ragnarsdottir M, KristjAnsdottir A, Ingvarsdottir I, Hannesson P, Torfason B, Cahalin L. Short-term changes in pulmonary function and respiratory movements after cardiac surgery via median sternotomy. Scand Cardiovasc J. 2004 Mar;38(1):46-52. doi: 10.1080/14017430310016658.

Reference Type BACKGROUND
PMID: 15204247 (View on PubMed)

Bruce J, Drury N, Poobalan AS, Jeffrey RR, Smith WC, Chambers WA. The prevalence of chronic chest and leg pain following cardiac surgery: a historical cohort study. Pain. 2003 Jul;104(1-2):265-73. doi: 10.1016/s0304-3959(03)00017-4.

Reference Type BACKGROUND
PMID: 12855337 (View on PubMed)

Kalso E, Mennander S, Tasmuth T, Nilsson E. Chronic post-sternotomy pain. Acta Anaesthesiol Scand. 2001 Sep;45(8):935-9. doi: 10.1034/j.1399-6576.2001.450803.x.

Reference Type BACKGROUND
PMID: 11576042 (View on PubMed)

Locke TJ, Griffiths TL, Mould H, Gibson GJ. Rib cage mechanics after median sternotomy. Thorax. 1990 Jun;45(6):465-8. doi: 10.1136/thx.45.6.465.

Reference Type BACKGROUND
PMID: 2392792 (View on PubMed)

Mazzeffi M, Khelemsky Y. Poststernotomy pain: a clinical review. J Cardiothorac Vasc Anesth. 2011 Dec;25(6):1163-78. doi: 10.1053/j.jvca.2011.08.001. Epub 2011 Sep 29. No abstract available.

Reference Type BACKGROUND
PMID: 21955825 (View on PubMed)

Meyerson J, Thelin S, Gordh T, Karlsten R. The incidence of chronic post-sternotomy pain after cardiac surgery--a prospective study. Acta Anaesthesiol Scand. 2001 Sep;45(8):940-4. doi: 10.1034/j.1399-6576.2001.450804.x.

Reference Type BACKGROUND
PMID: 11576043 (View on PubMed)

van Gulik L, Janssen LI, Ahlers SJ, Bruins P, Driessen AH, van Boven WJ, van Dongen EP, Knibbe CA. Risk factors for chronic thoracic pain after cardiac surgery via sternotomy. Eur J Cardiothorac Surg. 2011 Dec;40(6):1309-13. doi: 10.1016/j.ejcts.2011.03.039. Epub 2011 May 10.

Reference Type BACKGROUND
PMID: 21561786 (View on PubMed)

van Leersum NJ, van Leersum RL, Verwey HF, Klautz RJ. Pain symptoms accompanying chronic poststernotomy pain: a pilot study. Pain Med. 2010 Nov;11(11):1628-34. doi: 10.1111/j.1526-4637.2010.00975.x.

Reference Type BACKGROUND
PMID: 21044253 (View on PubMed)

Westerdahl E, Lindmark B, Bryngelsson I, Tenling A. Pulmonary function 4 months after coronary artery bypass graft surgery. Respir Med. 2003 Apr;97(4):317-22. doi: 10.1053/rmed.2002.1424.

Reference Type BACKGROUND
PMID: 12693792 (View on PubMed)

Hansen D, Dendale P, Berger J, Meeusen R. Rehabilitation in cardiac patients:what do we know about training modalities? Sports Med. 2005;35(12):1063-84. doi: 10.2165/00007256-200535120-00005.

Reference Type BACKGROUND
PMID: 16336009 (View on PubMed)

Alston RP, Pechon P. Dysaesthesia associated with sternotomy for heart surgery. Br J Anaesth. 2005 Aug;95(2):153-8. doi: 10.1093/bja/aei152. Epub 2005 May 13.

Reference Type BACKGROUND
PMID: 15894562 (View on PubMed)

Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J; ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J. 2005 Aug;26(2):319-38. doi: 10.1183/09031936.05.00034805. No abstract available.

Reference Type BACKGROUND
PMID: 16055882 (View on PubMed)

Roncada G. Osteopathic treatment leads to significantly greater reductions in chronic thoracic pain after CABG surgery: A randomised controlled trial. J Bodyw Mov Ther. 2020 Jul;24(3):202-211. doi: 10.1016/j.jbmt.2020.03.004. Epub 2020 Mar 17.

Reference Type DERIVED
PMID: 32825989 (View on PubMed)

Roncada G. Effects of osteopathic treatment on pulmonary function and chronic thoracic pain after coronary artery bypass graft surgery (OstinCaRe): study protocol for a randomised controlled trial. BMC Complement Altern Med. 2016 Nov 25;16(1):482. doi: 10.1186/s12906-016-1468-3.

Reference Type DERIVED
PMID: 27884147 (View on PubMed)

Other Identifiers

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09.07/cardio09.01

Identifier Type: -

Identifier Source: org_study_id

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