Study Of Factors Favoring The Onset Of Novo Atrial Fibrillation In The Immediate Aftermath Of Coronary Artery Bypass Surgery
NCT ID: NCT02042547
Last Updated: 2014-01-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
100 participants
OBSERVATIONAL
2010-09-30
Brief Summary
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Transthoracic cardiac echography will be done systematically, to measure among other things the size of the left atrium.
During surgery:
Surgery under extracorporeal circulation: tissue samples will be harvested from the right atrium (one before clamping of the aorta (T0= pre-ischemia sample), immediately before declamping of the aorta (T1= post-ischemia sample).
Surgery without extracorporeal circulation: tissue samples from the right atrium before CABG (T0) and a second sample after CABG (T1).
In parallel with the harvesting of cardiac tissue, blood samples will be taken at different times (H0, H3, H24) to correlate tissue data with systemic data. These will be taken by the anesthetists.
After the surgery:
Holter ECG will be set up for 7 days of continuous recording. Each patient will fill in an observation notebook. The biological samples will be analysed immediately and the biological data obtained will be recorded in the observation notebook.
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Patients about to undergo heart surgery
Tissue samples from the right atrium
Blood samples
Interventions
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Tissue samples from the right atrium
Blood samples
Eligibility Criteria
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Inclusion Criteria
* Patients covered by the national health insurance scheme
* Heart surgery (CABG) with and without extracorporeal circulation
* Elective or deferred emergency surgery
* Consecutive patients aged less than 80 years
Exclusion Criteria
* Patients over 18, under guardianship
* Patients who do not understand the study data
* Patients undergoing emergency surgery who therefore cannot be given or understand the explanations for the study (patients in shock, intubated patients with mechanical ventilation)
* History of heart surgery
* History of AF
* Treatment with Cordarone.
18 Years
79 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire Dijon
OTHER
Responsible Party
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Locations
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CHU de DIJON
Dijon, , France
Countries
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Other Identifiers
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LAURENT PARI 2010
Identifier Type: -
Identifier Source: org_study_id
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