Effect of Preoperative Stellate Ganglion Block on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting

NCT ID: NCT07271615

Last Updated: 2025-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-19

Study Completion Date

2026-07-31

Brief Summary

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The primary objective of this study is to determine the feasibility of preoperative stellate ganglion block in reducing the incidence of postoperative atrial fibrillation in patients undergoing CABG.

Detailed Description

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Conditions

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Adult Patients Undergoing CABG

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Control group(C group)

the best available treatment without block (usual care)

Group Type NO_INTERVENTION

No interventions assigned to this group

Stellate Ganglion Block(S group)

Ultrasound-guided stellate ganglion block with ropivacaine

Group Type OTHER

Stellate Ganglion Block

Intervention Type PROCEDURE

Ultrasound-guided stellate ganglion block with ropivacaine

Interventions

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Stellate Ganglion Block

Ultrasound-guided stellate ganglion block with ropivacaine

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* more than 18 years old
* undergoing CABG
* Provide informed consent

Exclusion Criteria

* History of prior cardiac surgery or atrial fibrillation ablation;
* Emergency coronary artery bypass grafting (CABG);
* Concomitant cardiac procedures (e.g., congenital heart disease repair, left ventricular reconstruction, valve surgery, or aortic surgery);
* Critical preoperative status requiring mechanical or pharmacological support before CABG;
* Left ventricular ejection fraction (LVEF) \<35%;
* History of atrial fibrillation (defined as a supraventricular tachyarrhythmia characterized by rapid and irregular atrial electrical activity);
* Significant mitral valve disease (mitral valve area \<1.5 cm² or regurgitant jet area \<4 cm²), significant aortic valve disease (valve area \<1.5 cm² or regurgitant jet-to-left ventricular outflow tract ratio \>25%);
* Severe left atrial enlargement (left atrial anteroposterior diameter \>55 mm);
* Poorly controlled hyperthyroidism;
* Conditions requiring radiotherapy, chemotherapy, or long-term hormonal therapy;
* Patients with known clinical contraindications to stellate ganglion block (SGB).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xijing Hospital

OTHER

Sponsor Role lead

Responsible Party

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Chong Lei, MD & phD

MD,phD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Xijing Hospital

Xi'an, Shaanxi, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Chong Lei

Role: CONTACT

18629011362

Facility Contacts

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Lini Wang, M.D.

Role: primary

86-152092345085

Chong Lei, PH.D., M.D.

Role: backup

86-18629011362

Other Identifiers

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KY20250716

Identifier Type: -

Identifier Source: org_study_id

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