Predictors of Postoperative Atrial Fibrillation After CABG

NCT ID: NCT05888168

Last Updated: 2023-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

15000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2024-05-01

Brief Summary

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This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.

Detailed Description

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Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.

Conditions

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Coronary Artery Disease Atrial Fibrillation New Onset

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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POAF

This group will consist of patients who have developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG).

CABG

Intervention Type PROCEDURE

All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.

Non-POAF

This group will consist of patients who have not developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG).

CABG

Intervention Type PROCEDURE

All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.

Interventions

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CABG

All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18 years or older.
* Patients who underwent CABG.

Exclusion Criteria

* Patients with a history of preoperative atrial fibrillation or other significant arrhythmias.
* Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG.
* Patients who cannot provide informed consent or lack adequate follow-up information.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kun Hua

OTHER

Sponsor Role lead

Responsible Party

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Kun Hua

Deputy Chief Surgeon

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Kun Hua, MD

Role: STUDY_CHAIR

Beijing Anzhen Hospital

Locations

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Beijing Anzhen Hospital

Beijing, , China

Site Status

Countries

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China

Other Identifiers

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2023065X

Identifier Type: -

Identifier Source: org_study_id

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