Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
NCT ID: NCT07163858
Last Updated: 2025-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
50 participants
INTERVENTIONAL
2025-10-06
2027-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Postural Group: hemodynamic management using postural mobilization (+/- noradrenaline)
In order to manage hemodynamics, postural mobilization will be applied by raising legs passively up to a 45° angle prior to any drug use (noradrenaline). If passive leg raising is not sufficient, noradrenaline will be used to stabilize hemodynamics,.
passive leg raising for hemodynamic management during open-heart coronary bypass grafting
Passive leg raising will be used in the experimental group in order to manage hemodynamics: legs will be raised to an angle of approx. 45°
Control group: use of noradrenaline only (no postural mobilization)
Noradrenaline will be used to manage hemodynamics. Passive leg raising will not be used in this group
Use of Noradrenaline only in control group
Noradrenaline will be used for hemodynamic management. Passive leg raising will not be used in this group
Interventions
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passive leg raising for hemodynamic management during open-heart coronary bypass grafting
Passive leg raising will be used in the experimental group in order to manage hemodynamics: legs will be raised to an angle of approx. 45°
Use of Noradrenaline only in control group
Noradrenaline will be used for hemodynamic management. Passive leg raising will not be used in this group
Eligibility Criteria
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Inclusion Criteria
* patient requiring isolated coronary bypass surgery
* Elective procedure or medical emergency
* First cardiac surgery
* Patient with an EF ≥30%
* Mandatory affiliation to a social security system
* Signed informed consent form
* Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure
Exclusion Criteria
* Contraindication to passive leg raising
* Patient in a life-threatening emergency
* History of cardiac surgery
* Bilateral iliac or common femoral artery occlusion
* EF \< 30%
* Pregnancy and breastfeeding
* Renal failure (GFR \< 40 ml/min/1.73 m²)
* Patient with bilateral thigh amputation
* Class III obesity BMI \> 40 kg/m²
18 Years
ALL
No
Sponsors
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Infirmerie Protestante de Lyon
OTHER
Responsible Party
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Locations
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Infirmerie Protestante de Lyon
Caluire-et-Cuire, Auvergne-Rhône-Alpes, France
Countries
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Central Contacts
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Other Identifiers
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ID-RCB: 2024-A00683-44
Identifier Type: OTHER
Identifier Source: secondary_id
IPL/01-2024
Identifier Type: -
Identifier Source: org_study_id
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