The Safe Early Mobilization on CABG

NCT ID: NCT07276971

Last Updated: 2025-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-01

Study Completion Date

2023-12-29

Brief Summary

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Aim: This study aimed to evaluate the effect of a Safe Early Mobilization Protocol (SEMP) developed for patients undergoing coronary artery bypass graft (CABG) surgery on patient outcomes.

Design: A single-center, parallel-group, randomized controlled trial. Methods: The study was conducted with 60 patients in 2023. The intervention group received a Safe Early Mobilization Protocol including bedside elevation, deep breathing and coughing exercises, sitting upright in bed, sitting on the edge of the bed, standing, ambulation, and sitting in a bedside chair from the day of surgery until the fourth postoperative day. The control group received routine mobilization care. Respiratory parameters, orthostatic hypotension (OH), orthostatic intolerance (OI), mobilization distance, anxiety level, and hospital stay were evaluated.

Detailed Description

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Conditions

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Coronary Artery Bypass Graft Nursing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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SEMP

A safe early mobilization protocol developed by the researchers was applied.

Group Type EXPERIMENTAL

The safe early mobilization protocol

Intervention Type OTHER

This protocol was developed to guide the early postoperative mobilization of patients undergoing coronary artery bypass graft surgery, covering the period from the day of surgery to the fourth postoperative day. Prior to mobilization, patients are evaluated using a checklist ensuring physical and environmental safety. On the day of surgery, following extubation by the responsible physician, six stages are applied: bed head elevation, deep breathing exercises, incentive spirometry, passive range of motion (ROM) exercises, sitting upright (90°), and sitting on the edge of the bed. On postoperative days 1-3, standing at the bedside, ambulation, and sitting on a chair are added. Target walking distances are 100-150 m on day 1, 200-250 m on day 2, and 300-350 m on day 3. Distances are measured by the researcher using a meter. The protocol concludes on the 4th postoperative day when the patient can ambulate independently.

Control group

The routine protocol used in the hospital was applied.

Group Type ACTIVE_COMPARATOR

Control Group

Intervention Type OTHER

Patients in the control group were informed about the current mobilization practices applied in the clinic before surgery. The morning after the surgery (the first day after the surgery), the patient is first seated in the bed, and in the second stage, he is made to sit on the edge of the bed with his feet touching the floor and is observed. In the third stage, the patient stands in an upright position and if there is no dizziness or blackout, the patient is seated on a chair next to the bed. The duration of sitting in the chair is determined depending on the general condition of the patient (pain, dizziness, blackout, nausea). On the 2nd and 3rd postoperative day, patients were contacted by nurses and care support staff while they had a chest tube; Then, the patient is mobilized only with his/her relative. There is no standard practice regarding how long patients should be mobilized during the day.

Interventions

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The safe early mobilization protocol

This protocol was developed to guide the early postoperative mobilization of patients undergoing coronary artery bypass graft surgery, covering the period from the day of surgery to the fourth postoperative day. Prior to mobilization, patients are evaluated using a checklist ensuring physical and environmental safety. On the day of surgery, following extubation by the responsible physician, six stages are applied: bed head elevation, deep breathing exercises, incentive spirometry, passive range of motion (ROM) exercises, sitting upright (90°), and sitting on the edge of the bed. On postoperative days 1-3, standing at the bedside, ambulation, and sitting on a chair are added. Target walking distances are 100-150 m on day 1, 200-250 m on day 2, and 300-350 m on day 3. Distances are measured by the researcher using a meter. The protocol concludes on the 4th postoperative day when the patient can ambulate independently.

Intervention Type OTHER

Control Group

Patients in the control group were informed about the current mobilization practices applied in the clinic before surgery. The morning after the surgery (the first day after the surgery), the patient is first seated in the bed, and in the second stage, he is made to sit on the edge of the bed with his feet touching the floor and is observed. In the third stage, the patient stands in an upright position and if there is no dizziness or blackout, the patient is seated on a chair next to the bed. The duration of sitting in the chair is determined depending on the general condition of the patient (pain, dizziness, blackout, nausea). On the 2nd and 3rd postoperative day, patients were contacted by nurses and care support staff while they had a chest tube; Then, the patient is mobilized only with his/her relative. There is no standard practice regarding how long patients should be mobilized during the day.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Hemodynamic stability, defined as:

Resting heart rate \<110/min

Mean arterial pressure between 60-110 mmHg

Oxygen saturation (SpO₂) \>88%

Receiving dopamine infusion ≤5 mcg/kg/min at the time of enrollment

No auditory, speech, or visual impairments

No neurological contraindications (e.g., cerebrovascular accident \[CVA\], ataxia, multiple sclerosis \[MS\])

No orthopedic contraindications that prevent mobilization (e.g., fractures or sequelae)

Provided informed consent to participate in the study

Age ≥18 years

Able to speak Turkish

Literate patients

Exclusion Criteria

Requirement for intra-aortic balloon pump (IABP) support

Postoperative cerebrovascular events

High-dose inotropic drug infusion in the early postoperative period:

Dopamine ≥10 mcg/kg/min

Norepinephrine ≥0.5 mcg/kg/min

Concurrent dopamine and norepinephrine infusion

Severe arrhythmias preventing mobilization, including:

Sinus tachycardia ≥120/min

Rapid atrial fibrillation

Ventricular tachycardia

Ventricular fibrillation

Advanced chronic obstructive pulmonary disease (COPD) or bronchiectasis

Diagnosed anxiety disorders
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hulya BULUT

OTHER

Sponsor Role lead

Lokman Hekim University

OTHER_GOV

Sponsor Role collaborator

Ankara Guven Hospital

UNKNOWN

Sponsor Role collaborator

Responsible Party

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Hulya BULUT

Prof. Dr.

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Guven Hospital

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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36970

Identifier Type: -

Identifier Source: org_study_id

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