Study to Evaluate the Impact of the Recovery Pathway on Postoperative Leght of Stay in Coronary Artery Bypass Surgery

NCT ID: NCT06713096

Last Updated: 2024-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

128 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-25

Study Completion Date

2025-12-31

Brief Summary

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This randomized and prospective trial aims to evaluate the implementation of a rapid recovery protocol for coronary artery bypass grafting (CABG) in a hospital serving patients from the Brazilian Unified Health System (Sistema Único de Saúde - SUS). The study will compare outcomes between two groups: patients receiving care under the rapid recovery protocol and those following the standard institutional care.

Primary Objective:

Compare postoperative hospital stay between the rapid recovery group and the usual care group.

Secondary Objectives:

Assess morbidity and mortality between both groups.

Evaluate patient satisfaction using validated tools.

Analyze incremental costs associated with both approaches.

Assess healthcare teams' learning progression regarding the protocol (Kirkpatrick method).

Evaluate adherence to rapid recovery protocol metrics by healthcare teams.

Measure changes in patient safety culture among healthcare professionals.

Hypothesis:

The null hypothesis assumes no difference in hospital stay between the two groups. The alternative hypothesis suggests that the rapid recovery protocol will reduce hospital stay compared to the standard care. Previous findings from Mejia et al. (2022) indicated a 40% reduction in postoperative hospital stay (from 13 to 7.8 days) for cardiac surgery patients under a rapid recovery protocol at the Heart Institute (InCor HCFMUSP).

This trial will provide critical insights into the applicability of enhanced recovery after surgery (ERAS) principles in cardiac surgery within the context of public healthcare, aiming to improve outcomes and optimize resource use.

Detailed Description

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Conditions

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Enhanced Recovery After Surgery Quality Improvement

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Usual care

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventional care

Group Type ACTIVE_COMPARATOR

Tempos Certos protocol

Intervention Type BEHAVIORAL

Improve the enhanced recovery by using the Tempos Certos Protocol by the multiprofissional team , using interventions known by science and recommended by scientists.

Interventions

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Tempos Certos protocol

Improve the enhanced recovery by using the Tempos Certos Protocol by the multiprofissional team , using interventions known by science and recommended by scientists.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Adult patients (\>18 years old)
* Undergoing isolated coronary artery bypass grafting (CABG) with elective or urgent status
* Signed informed consent form (ICF)

Exclusion Criteria

* Emergency patients
* Severe ventricular dysfunction (ejection fraction \<30%)
* Renal impairment (creatinine clearance \<30 mL/min)
* Atrial fibrillation or need for oral anticoagulation
* Moderate-to-severe anemia (hematocrit \<32%)
* STS risk score \>4%
* Patient and/or family disagreement with the protocol
* Failure to sign the informed consent form
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Sao Paulo General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gabrielle B Borgomoni, bsc, PhD student

Role: PRINCIPAL_INVESTIGATOR

Instituto do coração

Locations

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Hc Da Fmusp Instituto Do Coracao Incor Sao Paulo

São Paulo, São Paulo, Brazil

Site Status RECRUITING

Countries

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Brazil

Central Contacts

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Omar A V Mejia, md, PhD

Role: CONTACT

555+(11) 2661-5014

Facility Contacts

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Elaine Lagonegro, BSC

Role: primary

(11) 2661-5000

Other Identifiers

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50781921600000068

Identifier Type: REGISTRY

Identifier Source: secondary_id

528421059

Identifier Type: -

Identifier Source: org_study_id