Lean Seafood Intake and Postprandial Metabolism

NCT ID: NCT01708681

Last Updated: 2015-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2015-09-30

Brief Summary

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Despite numerous studies of meal components in humans, little is still known about how different meals influence on metabolism. The purpose of this study is to a gain knowledge of how a balanced test meal with either lean seafood (example:cod) or meat as the main protein source will:

1. affect the postprandial metabolism acutely (test-meal at beginning of the study)
2. affect the postprandial metabolism after 4 weeks controlled intervention (test meal at end of intervention period)
3. affect gut microbiota composition

Detailed Description

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Conditions

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Hyperlipidemias Nutritional and Metabolic Diseases Nutrition Disorders Metabolic Diseases Glucose Metabolism Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Investigators

Study Groups

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Lean seafood

Cross-over design, half of the subject will receive lean seafood in study period I and the other half in study period II

Group Type EXPERIMENTAL

Lean seafood

Intervention Type DIETARY_SUPPLEMENT

Meat, egg, milk

Intervention Type DIETARY_SUPPLEMENT

Meat, egg, milk

Cross-over design, half of the subject will receive meat, egg, milk in study period I and the other half in study period II

Group Type ACTIVE_COMPARATOR

Lean seafood

Intervention Type DIETARY_SUPPLEMENT

Meat, egg, milk

Intervention Type DIETARY_SUPPLEMENT

Interventions

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Lean seafood

Intervention Type DIETARY_SUPPLEMENT

Meat, egg, milk

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* 18-65 years of age
* Caucasian

Exclusion Criteria

* Smoking
* Diabetes
* Hysterectomy
* Abnormal bleeding last 6 months
* Use of medication that affects lipid and glucose metabolism
* Large (\>10%) alteration in body-weight the last 6 months
* Chronic, metabolic or acute disease or major surgery within last 3 months
* Dietary incompatibility with calcium supplementation and/ or seafood consumption (allergy, intolerance, dislike)
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Research Council of Norway

OTHER

Sponsor Role collaborator

National Institute of Nutrition and Seafood Research, Norway

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bjørn Liaset, Dr

Role: PRINCIPAL_INVESTIGATOR

NIFES

Locations

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National Institute of Nutrition and Seafood Research

Bergen, , Norway

Site Status

Countries

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Norway

References

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Aadland EK, Graff IE, Lavigne C, Eng O, Paquette M, Holthe A, Mellgren G, Madsen L, Jacques H, Liaset B. Lean Seafood Intake Reduces Postprandial C-peptide and Lactate Concentrations in Healthy Adults in a Randomized Controlled Trial with a Crossover Design. J Nutr. 2016 May;146(5):1027-34. doi: 10.3945/jn.115.229278. Epub 2016 Apr 20.

Reference Type DERIVED
PMID: 27099232 (View on PubMed)

Aadland EK, Lavigne C, Graff IE, Eng O, Paquette M, Holthe A, Mellgren G, Jacques H, Liaset B. Lean-seafood intake reduces cardiovascular lipid risk factors in healthy subjects: results from a randomized controlled trial with a crossover design. Am J Clin Nutr. 2015 Sep;102(3):582-92. doi: 10.3945/ajcn.115.112086. Epub 2015 Jul 29.

Reference Type DERIVED
PMID: 26224298 (View on PubMed)

Related Links

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Other Identifiers

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2012/1084/REK vest

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

NIFES-001

Identifier Type: -

Identifier Source: org_study_id

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