An Assessment of the Feasibility and Safety of Conservative Oxygen Therapy in Critically Ill Patients
NCT ID: NCT01684124
Last Updated: 2013-07-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1/PHASE2
105 participants
INTERVENTIONAL
2012-03-31
2013-03-31
Brief Summary
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Detailed Description
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2. Deliver a conservative oxygen therapy protocol while in ICU (a time frame on average of 10 days)
3. Target an oxygen saturation between 90 and 92%
4. Adjust FiO2 to achieve target SaO2 at all times
5. Assess percentage of time patient is within target
6. Assess for safety of this approach
Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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standard care
normal treatment
standard care
conservative O2 therapy
a value of 90-92% O2 saturation will be targeted
conservative O2 therapy
target lower O2 saturation
Interventions
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conservative O2 therapy
target lower O2 saturation
standard care
Eligibility Criteria
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Inclusion Criteria
* expected to be ventilated until the day after tomorrow (a tiem frame of, on average 48 hours)
Exclusion Criteria
* carbon monoxide poisoning
* necrotizing fasciitis
18 Years
90 Years
ALL
No
Sponsors
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Austin Health
OTHER_GOV
Responsible Party
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Rinaldo Bellomo
Director of ICU Research
Locations
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Austin Hospital
Melbourne, Victoria, Australia
Countries
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References
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Eastwood GM, Tanaka A, Espinoza ED, Peck L, Young H, Martensson J, Zhang L, Glassford NJ, Hsiao YF, Suzuki S, Bellomo R. Conservative oxygen therapy in mechanically ventilated patients following cardiac arrest: A retrospective nested cohort study. Resuscitation. 2016 Apr;101:108-14. doi: 10.1016/j.resuscitation.2015.11.026. Epub 2015 Dec 21.
Other Identifiers
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AICU2012-008
Identifier Type: -
Identifier Source: org_study_id
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