Feeling of Being in Control of One's Own Action

NCT ID: NCT01312649

Last Updated: 2025-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

198 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-04-30

Study Completion Date

2017-07-04

Brief Summary

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The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.

Detailed Description

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Conditions

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Schizophrenia Bipolar Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Arm 1

Healthy volunteers

Group Type EXPERIMENTAL

Experimental psychology methods (computer tests)

Intervention Type BEHAVIORAL

Arm 2

Schizophrenia with history of delusions of control

Group Type EXPERIMENTAL

Experimental psychology methods (computer tests)

Intervention Type BEHAVIORAL

Arm 3

Schizophrenia without history of delusions of control

Group Type EXPERIMENTAL

Experimental psychology methods (computer tests)

Intervention Type BEHAVIORAL

Arm 4

Bipolar disorders

Group Type EXPERIMENTAL

Experimental psychology methods (computer tests)

Intervention Type BEHAVIORAL

Arm 5

Matched healthy controls

Group Type ACTIVE_COMPARATOR

Experimental psychology methods (computer tests)

Intervention Type BEHAVIORAL

Interventions

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Experimental psychology methods (computer tests)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
* 18-55 years old

Exclusion Criteria

* Past history affecting CNS
* Invalidating sensory disorders
* Intake of psychotropic drugs, except for patients
* Intake of benzodiazepines
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anne GIERSCH, MD

Role: STUDY_DIRECTOR

Hôpitaux Universitaires de Strasbourg

Locations

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Pôle de Psychiatrie - Hôpital civil

Strasbourg, , France

Site Status

Countries

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France

References

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Turgeon M, Giersch A, Delevoye-Turrell Y, Wing AM. Impaired predictive timing with spared time interval production in individual with schizophrenia. Psychiatry Res. 2012 May 15;197(1-2):13-8. doi: 10.1016/j.psychres.2012.03.003. Epub 2012 Apr 11.

Reference Type RESULT
PMID: 22497958 (View on PubMed)

Other Identifiers

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4880

Identifier Type: -

Identifier Source: org_study_id

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