The Effect of Sertindole on Sensory Gating and Cognition in Schizophrenic Patients
NCT ID: NCT00629252
Last Updated: 2012-09-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
14 participants
INTERVENTIONAL
2008-02-29
2012-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
SINGLE
Study Groups
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1
Schizophrenic patients treated with sertindole
Sertindole
oral 12-20 mg/day
2
Schizophrenic patients treated with risperidone
Risperidone
oral 2-6mg / day
3
Healthy controls without any treatment.
No interventions assigned to this group
Interventions
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Sertindole
oral 12-20 mg/day
Risperidone
oral 2-6mg / day
Eligibility Criteria
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Inclusion Criteria
* Selected and treated in respect of the SPC (20 mg Serdolect max. and population at risk will be excluded)
Exclusion Criteria
* DSM IV Axis II disorders: Lifetime DSM IV diagnosis of personality disorder.
* ECG: QTc-interval \>450 msec.
* Systolic blood pressure \<100 mmHg
* Bradycardia (Hf \< 50/Min) und Arrhythmias
* Hypokalemia or Hypomagnesemia
18 Years
40 Years
ALL
Yes
Sponsors
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University Hospital of Psychiatry, Department Neuropsychopharmacology and Brain Imaging
OTHER
H. Lundbeck A/S
INDUSTRY
University of Zurich
OTHER
Responsible Party
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Principal Investigators
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Franz X. Vollenweider, Prof. Dr. med.
Role: PRINCIPAL_INVESTIGATOR
University Hospital of Psychiatry, Department Neuropsychopharmacology and Brain Imaging
Locations
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University Hospital of Psychiatry, Department Neuropsychopharmacology and Brain Imaging
Zurich, Canton of Zurich, Switzerland
Countries
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Other Identifiers
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E-11/2007
Identifier Type: -
Identifier Source: secondary_id
2007DR1253
Identifier Type: -
Identifier Source: secondary_id
98_PPI-P50
Identifier Type: -
Identifier Source: org_study_id
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