Changes in Brain Synchronization During Perceptual and Linguistic Tasks in Schizophrenic Patients

NCT ID: NCT01550211

Last Updated: 2012-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-03-31

Brief Summary

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This study aims to identify electrophysiological correlates of impaired perceptual and linguistic processes in chronic schizophrenic patients, un-medicated first-episode schizophrenic patients and their healthy relatives.

Following administrating some questionnaires (demographic details and psychiatric history questionnaire, handedness questionnaire, reading abilities test and positive and negative symptoms questionnaire) and performing a perception test and a verbal abstract intelligence test, participants will conduct a brain scan during a series of perceptual and linguistic tasks.

Detailed Description

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Conditions

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Schizophrenic Patients

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Students

Healthy students from Bar-Ilan University

Magnetoencephalograph (MEG)

Intervention Type DEVICE

Conducting a brain scan during a series of perceptual and linguistic tasks

Schizophrenic patients' relatives

Healthy family members (parents or siblings) of the schizophrenic participants (chronic and naive)

Magnetoencephalograph (MEG)

Intervention Type DEVICE

Conducting a brain scan during a series of perceptual and linguistic tasks

Naive schizophrenic patients

Naive patients with a diagnosis of schizophrenia, a history of only one psychotic episode and un-medicated

Magnetoencephalograph (MEG)

Intervention Type DEVICE

Conducting a brain scan during a series of perceptual and linguistic tasks

Chronic schizophrenia patients

Chronic patients with a diagnosis of schizophrenia and a history of more than one psychotic episode

Magnetoencephalograph (MEG)

Intervention Type DEVICE

Conducting a brain scan during a series of perceptual and linguistic tasks

Interventions

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Magnetoencephalograph (MEG)

Conducting a brain scan during a series of perceptual and linguistic tasks

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Hebrew native speakers.
* Diagnosis of schizophrenia with a history of more than one episode.
* Capable and willing to provide informed consent.


* Hebrew native speakers.
* Diagnosis of schizophrenia with a history of only one episode and unmedicated.
* Capable and willing to provide informed consent.


* Hebrew native speakers.
* Without any psychiatric history.
* Have a child and/or a sibling with schizophrenia.


* Hebrew native speakers.
* Without any psychiatric history.

Exclusion Criteria

* Left handedness.
* Reading disability.
* Visual perception disability.
* Brain damage and/or a history of seizures.
* Impaired intelligence.
* Metal implants.


* Psychiatric history.
* Left handedness.
* Reading disability.
* Visual perception disability.
* Brain damage and/or a history of seizures.
* Impaired intelligence.
* Metal implants.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Bar-Ilan University, Israel

OTHER

Sponsor Role collaborator

Shalvata Mental Health Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hilik Levkovitz, Professor

Role: PRINCIPAL_INVESTIGATOR

Shalvata MHC

Locations

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Shalvata MHC

Hod HaSharon, , Israel

Site Status

Countries

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Israel

Central Contacts

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Maor Zeev-Wolf, M.A.

Role: CONTACT

972-50-7737032

Facility Contacts

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Maor Zeev-Wolf, M.A.

Role: primary

972-50-7737032

Other Identifiers

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SHA-0001-12

Identifier Type: -

Identifier Source: org_study_id

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