Mothers With a History of Depression and Their 10-14 Year Old Daughters

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

240 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-02-29

Study Completion Date

2011-04-30

Brief Summary

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The purpose of this study is to investigate risk factors associated with depression and how such factors might be transmitted cross-generationally. The investigators are conducting an integrative assessment of emotion regulation and stress reactivity in a group of mothers with and without a history of depression and their daughters.

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Detailed Description

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The purpose of this study is to investigate risk factors associated with depression and how such factors might be transmitted cross-generationally. We are conducting an integrative assessment of emotion regulation and stress reactivity in a group of mothers with and without a history of depression and their daughters. We use a range of methodologies to evaluate these processes, including self-report measures, information-processing performance, HPA-axis functioning and reactivity, and neural responses to emotional stimuli following exposure to stressful experiences.

Conditions

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Depression Depressive Disorder, Major

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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children at risk for depression

children at familial risk for depression

No intervention

Intervention Type OTHER

there is no intervention for this study

Interventions

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No intervention

there is no intervention for this study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Eligible mothers must read and speak English fluently and have a child between the ages of 9 and 15 years old.
* Mothers must either have no history of psychopathology or have a history of depression during their child's lifetime.

Exclusion Criteria

* Eligible mothers cannot:

* currently be in treatment for drug or alcohol abuse
* have significant symptomatology related to psychopathology outside of depression
* have a medical history of neurological injury or impairment.
* Mothers who meet the requirements for inclusion in the control group must not have a history of any Axis I disorder.

Minimum Eligible Age

9 Years

Maximum Eligible Age

15 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes