The Effect of Obesity on Growth Hormone Response to Anaerobic Exercise

NCT ID: NCT01070589

Last Updated: 2012-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-02-28

Study Completion Date

2012-07-31

Brief Summary

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The aim of the present study is to asses the effect of obesity on anaerobic exercise's growth hormone (GH) response.

Detailed Description

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Exercise is a potent physiological stimulator of growth hormone (GH) release. GH is an important factor in the distribution of fat and lean tissue in the body. Previous studies suggested that the GH response to aerobic exercise may be attenuated by obesity. The effect of obesity on GH response to anaerobic effort is unclear. The aim of the present study is to asses the effect of obesity on anaerobic exercise's GH response. We will recruit 12 obese (BMI \> 30) healthy adults and 12 age and gender matched normal weight (BMI \< 25) controls. All the participants will conduct a "wingate" anaerobic test (30 seconds of intense effort against resistance calculated by the individual's body weight). Blood sample for GH level will be collected at 5 different time (0, 20, 30, 40 and 60 minutes after the test). We will compare the GH response in the two groups.

Conditions

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Obesity

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1: Obese

BMI\>30

No interventions assigned to this group

Group 2: control

Group 2:Normal weight (BMI \<25). age and gender matched.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Healthy female
* Age 18-40

Exclusion Criteria

* Male
* Age \<18, \>40
* Heart, Liver, Kidney or Hypophyseal disease
* Medications that may alter GH secretion (eg Steroids, Eltroxin)
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Meir Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Allon Eliakim, MD

Role: PRINCIPAL_INVESTIGATOR

Meir Medical Center

Locations

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Meir Medical Center

Kfar Saba, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Noa rakover klein, MD

Role: CONTACT

972-77-4920014

Facility Contacts

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Noa rakover klein, MD

Role: primary

974-9-7472630

Other Identifiers

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MMC01922009CTIL

Identifier Type: -

Identifier Source: org_study_id

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