Mindfulness Based Cognitive Therapy for Recurrent Depression

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-01-31

Study Completion Date

2011-01-31

Brief Summary

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The purpose of this study is to investigate the effectiveness and possible mediating factors of Mindfulness Based Cognitive Therapy (MBCT) for recurrent depression.

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Detailed Description

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Mindfulness Based Cognitive Therapy (MBCT) is a 8 session group intervention and is well described by several authors.

Previous studies showed Mindfulness Based Cognitive Therapy (MBCT) to be effective to prevent relapse in patients with recurrent depression and 3 or more previous depressive episodes.

Study aims are:

1. to replicate previous findings in The Netherlands, by a research team which did not develop the intervention
2. to investigate if MBCT is applicable for patients with recurrent depression and current depressive symptoms
3. to examine possible mediators of treatment effect and predictors of relapse in the year following the treatment

In this study, patients are randomly assigned to a MBCT intervention group or a waiting list control group. Patients allocated to the waiting list control condition will receive the MBCT course three months later. All patients who participated in a MBCT training will be assessed during the year following the completion of the MBCT course. We aim to include about 220 patients.

Conditions

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Depressive Disorder, Major

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Mindfulness Based Cognitive Therapy

Group Type EXPERIMENTAL

Mindfulness Based Cognitive Therapy

Intervention Type BEHAVIORAL

8-weeks group based intervention of mindfulness and cognitive behavioural techniques

Waiting list control group

3-month waiting list group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Mindfulness Based Cognitive Therapy

8-weeks group based intervention of mindfulness and cognitive behavioural techniques

Intervention Type BEHAVIORAL

Other Intervention Names

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MBCT

Eligibility Criteria

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Inclusion Criteria

* 3 or more previous depressive episodes
* if treated with medication: constant dose of at least 6 weeks

Exclusion Criteria

* Bipolar Disorder
* Psychotic disorder
* Neurological or somatic illness affecting depression or outcome measures
* Current alcohol or drugs dependency
* Acute need of psychiatric treatment

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No