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Psychophysiological Correlates of Mindfulness Based Cognitive Therapy (MBCT) in Recurrent Depression

NCT ID: NCT00974077

Last Updated: 2014-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-09-30

Study Completion Date

2011-07-31

Brief Summary

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The study investigates cognitive attention, rumination and psychophysiological (EEG) processes in healthy subjects and remitted patients with at least three previous depressive episodes. The investigators expect that Mindfulness Based Cognitive Therapy prevents future depressive episodes and has influence on cognitive and psychophysiological measures.

Detailed Description

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Conditions

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Depression

Keywords

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recurrent depression, mindfulness training attention Evoked EEG potentials Relapse prevention in recurrent depression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Wait List Control

Patients do ot receive psychotherapy. The wait list control group will be assessed according to study protocol and offered MBCT after 6 month

Group Type OTHER

Waiting List Control

Intervention Type OTHER

Patients receive MBCT with a delay of 6 months.

Mindfulness Based Cognitive Therapy

The published protocol of MBCT will be used. This is an eight week group program. Participants learn mindfulness techniques but also cognitive techniques to prevent new depressive episodes

Group Type EXPERIMENTAL

Mindfulness Based Cognitive Therapy

Intervention Type BEHAVIORAL

Group treatment over 8 weeks with training in meditation, stress regulation, shift attention, stay present, in addition with cognitive and behavioral strategies (following Williams et al. Manual 2002)

Interventions

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Mindfulness Based Cognitive Therapy

Group treatment over 8 weeks with training in meditation, stress regulation, shift attention, stay present, in addition with cognitive and behavioral strategies (following Williams et al. Manual 2002)

Intervention Type BEHAVIORAL

Waiting List Control

Patients receive MBCT with a delay of 6 months.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* recurrent depression with at least 3 previous MD-episodes, currently remitted (no symptoms)

Exclusion Criteria

* current depression
* lifetime schizophrenia
* bipolar or schizoaffective disorder
* any neurological disorders
* other psychopathology during last 3 years
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital Tuebingen

OTHER

Sponsor Role lead

Responsible Party

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Prof. Dr. Martin Hautzinger

University Professor of Clinical Psychology and Psychotherapy

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Martin Hautzinger, PhD

Role: PRINCIPAL_INVESTIGATOR

Eberhard Karls University

Locations

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Department of Psychology University of Tuebingen

Tübingen, , Germany

Site Status

Countries

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Germany

References

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Bostanov V, Keune PM, Kotchoubey B, Hautzinger M. Event-related brain potentials reflect increased concentration ability after mindfulness-based cognitive therapy for depression: a randomized clinical trial. Psychiatry Res. 2012 Oct 30;199(3):174-80. doi: 10.1016/j.psychres.2012.05.031. Epub 2012 Jul 6.

Reference Type RESULT
PMID: 22771173 (View on PubMed)

Keune PM, Bostanov V, Hautzinger M, Kotchoubey B. Approaching dysphoric mood: state-effects of mindfulness meditation on frontal brain asymmetry. Biol Psychol. 2013 Apr;93(1):105-13. doi: 10.1016/j.biopsycho.2013.01.016. Epub 2013 Feb 11.

Reference Type RESULT
PMID: 23410762 (View on PubMed)

Other Identifiers

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HA1399/16-1

Identifier Type: -

Identifier Source: org_study_id