Red Cell Mass and Plasma Volume Measurements in Elderly Men and Women With Anemia

NCT ID: NCT01011361

Last Updated: 2016-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

5 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-04-30

Study Completion Date

2011-06-30

Brief Summary

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On the basis that the clinical consequences of seemingly trivial levels of anemia are surprisingly severe, this study investigates if hemoglobin concentration accurately represents the underlying red cell mass in elderly patients with unresolved anemia.

Detailed Description

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For the study, the routine clinical measurement of hemoglobin will be compared to true red cell mass and plasma volume in elderly patients with anemia.

Conditions

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Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* 65 and older
* Anemia (hemoglobin \< 13 g/dL in men or \< 12 g/dL in women)
* Outpatient at either the Stanford Health Care (SHC) Medical Center or VA Palo Alto Health Care System

Exclusion Criteria

* Body mass index (BMI):

* \< 18.5 kg/m2
* \> 35 kg/m2
* Palpable splenomegaly
* Contraindication to RBC mass/plasma volume testing
* On any experimental pharmacologic agent in the prior 2 months
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Stanley L Schrier

Professor of Medicine (Hematology), Emeritus

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stanley L Schrier, MD

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Locations

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Stanford University School of Medicine

Stanford, California, United States

Site Status

Countries

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United States

Other Identifiers

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SU-07302009-3480

Identifier Type: OTHER

Identifier Source: secondary_id

IRB-16209

Identifier Type: -

Identifier Source: org_study_id

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