Assesment of Treatment Outcomes of Aquired Aplastic Anemia in Children : A Retrospective and Prospective Cohort

NCT ID: NCT07131878

Last Updated: 2025-08-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

35 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-15

Study Completion Date

2028-01-15

Brief Summary

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The goal of this observational study is to to assess of treatment Outcomes of Aquired Aplastic Anemia in children

Detailed Description

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This study will be conducted to investigate the clinical outcomes, and treatment modalities of patients diagnosed with aquired aplastic anaemia at Assiut University children Hospital

The main question it aims to answer is:

Conditions

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Aplastic Anaemia (AA)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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patient diagnosed with aplastic anemia from July 2023 to sept 2025

No interventions assigned to this group

patient diagnosed with aplastic anemia from Sept 2025 to July 2026

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Children aged 1-18 years diagnosed with acquired aplastic anemia, as confirmed by bone marrow examination and fulfilling diagnostic criteria (e.g., bone marrow cellularity \<25% and at least two of the following: absolute neutrophil count \<500/μL, platelet count \<20,000/μL, absolute reticulocyte count \<60,000/μL)123.
* The bone marrow biopsy should be compitable with diagnosis
* Diagnosed and/or treated at Assiut University Children's Hospital between Agust 2023 and Augst 2026.
* Patients with complete medical records, including diagnostic, laboratory, and treatment data

Exclusion Criteria

* Patients with inherited bone marrow failure syndromes (e.g., Fanconi anemia, dyskeratosis congenita) as confirmed by genetic testing or family history21.
* Patients with incomplete or missing essential data in their medical records.
* Patients diagnosed outside the specified study period or managed primarily at other institutions.
* Patinets with neoplastic or granulomatous disease involving the bone marrow, systemic lupus erythematosus, AIDS, hypersplenism or other conditions associated with pancytopenia such as myelodysplastic syndrome,and paroxysmal nocturnal hemoglobinuria.
* Patients exposed to antineoplastic chemotherapy or radiotherapy were excluded
Minimum Eligible Age

1 Year

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Marwa Mohamed Abozaid

Resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Marwa M Abozaid, master

Role: CONTACT

+201146679786

Other Identifiers

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Aquired Aplastic Anemia ttt

Identifier Type: -

Identifier Source: org_study_id

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