Etiology of Anemia

NCT ID: NCT00302939

Last Updated: 2019-08-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-01-31

Study Completion Date

2010-12-31

Brief Summary

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This study looks at the causes of anemia in adults of all ages who are referred by their primary care physician.

Detailed Description

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This study is being done to determine if the range of causes of anemia changes with advancing age. The goal of this study is to apply research methods to see if causes of anemia can be determined in patients where a clear cause is not found with routine clinical testing available to all patients in physician offices.

Participants in this study will be evaluated at the NIA-ASTRA unit at Harbor Hospital in Baltimore. Testing will consist of both diagnostic and research blood and urine testing along with history and physical exam. An optional bone marrow aspirate or aspirate and biopsy may be performed if the patient permits and it is indicated for either research or clinical diagnostic purposes. All study information supporting a specific diagnosis will be provided to the patient and, at their request, to their primary care physician if specific treatment is indicated.

Conditions

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Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* Hemoglobin (Hgb) less than 13 in males and females

Exclusion Criteria

* Pregnant or nursing women
* Participation within the past six weeks in another research study which the Principal Investigator believes is incompatible with this study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Aging (NIA)

NIH

Sponsor Role lead

Responsible Party

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National Institute on Aging

Principal Investigators

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William Ershler, MD

Role: PRINCIPAL_INVESTIGATOR

NIA/NIH

Locations

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National Institute on Aging

Baltimore, Maryland, United States

Site Status

Countries

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United States

References

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Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004 Oct 15;104(8):2263-8. doi: 10.1182/blood-2004-05-1812. Epub 2004 Jul 6.

Reference Type BACKGROUND
PMID: 15238427 (View on PubMed)

Artz AS, Fergusson D, Drinka PJ, Gerald M, Bidenbender R, Lechich A, Silverstone F, McCamish MA, Dai J, Keller E, Ershler WB. Mechanisms of unexplained anemia in the nursing home. J Am Geriatr Soc. 2004 Mar;52(3):423-7. doi: 10.1111/j.1532-5415.2004.52116.x.

Reference Type BACKGROUND
PMID: 14962159 (View on PubMed)

Other Identifiers

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AG0062

Identifier Type: -

Identifier Source: org_study_id

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