Search for Biomarkers in Human Glaucoma: Lymphocytes Alterations and Rate of Progression

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-06-30

Study Completion Date

2008-06-30

Brief Summary

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The aim of this study was to evaluate the lymphocyte phenotype in primary open- angle glaucoma (POAG) patients compared to healthy subjects of the same age, in order to confirm the importance of immune responses in glaucoma and the possible correlation to the severity of the disease.

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Detailed Description

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Conditions

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Glaucoma, Open-Angle

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Glaucoma patients

POAG patients selected by an ophthalmologist from the Glaucoma Service, Ophthalmology Institute, University of Parma

No interventions assigned to this group

Healthy

healthy subjects with negative history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection, (e) diabetes, and (f) systemic inflammation

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of primary open-angle glaucoma
* age between 19 an 85 years old

Exclusion Criteria

* age less than 19 or more than 85 yrs
* positive history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection and (e) diabetes, (f)systemic inflammation

Minimum Eligible Age

19 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No