Severe Intraocular Infection

NCT ID: NCT02818062

Last Updated: 2016-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

263 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2011-09-30

Brief Summary

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The host-immune reaction to infection is essential for the comprehension of the disease and the development of new therapies.

The aim of the study is to describe intraocular cytokines network in aqueous humor using multiplex immunoassay, during severe intraocular infection.

Detailed Description

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Conditions

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Endophthalmitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Endophthalmitis

The diagnosis of endophthalmitis was made on the basis of clinical features including pain, decreased visual acuity (VA), diffuse bulbar conjunctival hyperaemia, chemosis, inflammation of the anterior segment and posterior segment inflammation (all patients had vitreous infiltration diagnosed by biomicroscopy or ophthalmic ultrasound).

Cytokines dosage in Aqueous humor

Intervention Type BIOLOGICAL

Specify details not covered in associated Arm Description.

Cataract (Control)

Controls were patients who underwent cataract surgery.

Cytokines dosage in Aqueous humor

Intervention Type BIOLOGICAL

Specify details not covered in associated Arm Description.

Interventions

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Cytokines dosage in Aqueous humor

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Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Post-operative endophthalmitis
* Cataract

Exclusion Criteria

* None
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Service d'Ophtalmologie, Hôpital Pasteur

Colmar, , France

Site Status

Service d'Ophtalmologie, Hôpital Général de Dijon

Dijon, , France

Site Status

Service d'Ophtalmologie, Hôpital Michallon

Grenoble, , France

Site Status

Service d'Ophtalmologie, Centre Hospitalier de Mulhouse

Mulhouse, , France

Site Status

Service d'Ophtalmologie, CHU de Nancy

Nancy, , France

Site Status

Service d'Ophtalmologie, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg

Strasbourg, , France

Site Status

Service d'Ophtalmologie, Hôpital de Brabois

Vandœuvre-lès-Nancy, , France

Site Status

Countries

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France

Other Identifiers

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3964

Identifier Type: -

Identifier Source: org_study_id

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