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Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

NCT ID: NCT06184620

Last Updated: 2023-12-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

263 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-12-01

Study Completion Date

2023-03-30

Brief Summary

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The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

Detailed Description

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Patients clinically diagnosed with Primary angle-closure glaucoma (PACG) and normal control patients from December 2020 to January 2022 were enrolled in this study.

Conditions

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Primary Angle Closure Glaucoma

Keywords

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primary angle closure glaucoma UBM lens zonule

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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PACG group

All patients in the experimental group met the diagnostic criteria of primary angle-closure glaucoma in the Chinese Glaucoma Guidelines(2020).

No interventions assigned to this group

control group

The depth of the anterior chamber is normal, and the whole corner of the chamber is open; The cup-to-plate ratio is less than 0.5; No family history of glaucoma

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* The depth of the anterior chamber is normal, and the whole corner of the chamber is open;
* The cup-to-plate ratio is less than 0.5;
* No family history of glaucoma.

Exclusion Criteria

* Previous history of trauma or internal eye surgery in both eyes or one eye;
* Used "pilocarpine", "atropine" and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week;
* Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.;
* Can not cooperate with UBM and Angle scopy;
* Refuse to participate in this researcher.
Minimum Eligible Age

47 Years

Maximum Eligible Age

91 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Guangfu Dang

OTHER

Sponsor Role lead

Responsible Party

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Guangfu Dang

professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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guangfu Dang

Jinan, Shandong, China

Site Status

Countries

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China

Other Identifiers

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YXLL-KY-2023(047)

Identifier Type: -

Identifier Source: org_study_id