Evaluation of Plasma Catecholamine Concentration During Surgery

NCT ID: NCT00948181

Last Updated: 2009-07-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

8 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Study Completion Date

2010-09-30

Brief Summary

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Stress during surgery leads to significant increase in plasma catecholamine concentrations in surgeons, anesthesiologists, and patients.

Detailed Description

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Hypothesis: Resection of pheochromocytomas can lead to more than normal stress in surgeons and because of abrupt hemodynamic changes in patients as well in anesthesiologists. Measurements of catecholamine concentrations at baseline, prior to surgery during and after surgery, are to be performed to test this hypothesis.

Conditions

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Stress

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Surgeon

To detect the degree of intraoperative stress, venous blod will be drawn from one surgeon during 8 pheochromocytoma resections.

No interventions assigned to this group

Anesthesiologist

To detect the degree of intraoperative stress, venous blood will be drawn from one anesthesiologist during 8 pheochromocytoma resections.

No interventions assigned to this group

Patients with pheochromocytoma

Venous blood will be drawn from 8 patients with pheochromocytoma during tumor resection.

No interventions assigned to this group

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universität Duisburg-Essen

OTHER

Sponsor Role collaborator

Kliniken Essen-Mitte

OTHER

Sponsor Role lead

Responsible Party

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Kliniken Essen-Mitte

Principal Investigators

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Harald Groeben, M.D.

Role: PRINCIPAL_INVESTIGATOR

Kliniken Essen-Mitte

Locations

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Prof. Dr. Harald Groeben

Essen, , Germany

Site Status

Countries

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Germany

References

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Unger N, Pitt C, Schmidt IL, Walz MK, Schmid KW, Philipp T, Mann K, Petersenn S. Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass. Eur J Endocrinol. 2006 Mar;154(3):409-17. doi: 10.1530/eje.1.02097.

Reference Type BACKGROUND
PMID: 16498054 (View on PubMed)

Schuttler J, Westhofen P, Kania U, Ihmsen H, Kammerecker S, Hirner A. [Quantitative assessment of catecholamine secretion as a rational principle of anesthesia management in pheochromocytoma surgery]. Anasthesiol Intensivmed Notfallmed Schmerzther. 1995 Oct;30(6):341-9. doi: 10.1055/s-2007-996507. German.

Reference Type BACKGROUND
PMID: 8541435 (View on PubMed)

Other Identifiers

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2009061

Identifier Type: -

Identifier Source: org_study_id

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