Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
60 participants
INTERVENTIONAL
2015-01-31
2018-06-30
Brief Summary
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Patient are randomized to receive the investigators' standard moderate dose sufentanil (bolus 1microgram/kg and propofol 0.03 mg/kg/min) or low dose sufentanil (bolus 0.5 microgram/kg and propofol 0.06 mg/kg/min).
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Detailed Description
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Patients are monitored before induction of anesthesia. Propofol is started on the randomized infusion rate. Sufentanil bolus are given according to randomization. BIS level is followed. Time to reach BIS \< 50 is monitored. BIS after 30, 60 and 90 minutes are registered. Lowest BIS during surgery are registered. Total amounts of sufentanil and propofol recorded.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
SINGLE
Study Groups
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Sufentanil I
Randomized arm "moderate" sufentanil I: bolus 1 microgram/kg propofol I: infusion 0.03 mg/kg/min
Sufentanil I
bolus dose of sufentanil 1 microgram/kg
Propofol I
Continued dose of propofol 0.03 mg/kg/min
Sufentanil II
Randomized arm "low" sufentanil II bolus 0.5 microgram/kg propofol II: infusion 0.06 mg/kg/min
Sufentanil II
bolus dose of sufentanil 0.5 microgram/kg
Propofol II
Continued dose of propofol 0.06 mg/kg/min
Interventions
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Sufentanil I
bolus dose of sufentanil 1 microgram/kg
Sufentanil II
bolus dose of sufentanil 0.5 microgram/kg
Propofol I
Continued dose of propofol 0.03 mg/kg/min
Propofol II
Continued dose of propofol 0.06 mg/kg/min
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients with expected longer postoperative ventilation time
* Patients allergic to sufentanil and or propofol
* Participation in other projects
* Pregnancy
16 Years
90 Years
No
Sponsors
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Aarhus University Hospital
OTHER
Responsible Party
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Carl-Johan Jakobsen
Consultant Anesthesiologist, Ass professor
Other Identifiers
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SATA-1
Identifier Type: -
Identifier Source: org_study_id
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