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Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients

NCT ID: NCT00850148

Last Updated: 2012-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2008-05-31

Study Completion Date

2009-09-30

Brief Summary

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This study will be performed on patients who come to labbafinejad ophthalmic clinic from 20 March 2008. Keratoconus diagnosis will be determined by clinical finding in slit lamp, keratometery and topographic characteristics. Patients will be randomly placed in group A and B. In group A, Anwar surgical method and in B, Melles surgical method, will be done. This is not a blind study due to surgeons' knowledge. All patients will receive Btamethazone drop and Chloramphenicol every 6 hours and will be tapered in two months. In the end anatomical results, complications, BCVA, UCVA, astigmatism, endothelial cell numbers will be compared in two groups by using specular microscopy. Contrast sensivity, central corneal diameter, interface wrinkling and opacity will be measured by metrovison, Confoscan, Photoslit in months 3, 6, 12, respectively and will be evaluated afterwards.

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Detailed Description

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Conditions

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Keratoconus

Study Groups

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Melles

Group Type EXPERIMENTAL

Melles

Intervention Type PROCEDURE

Melles surgical method

Anwar

Group Type EXPERIMENTAL

Anwar

Intervention Type PROCEDURE

Anwar surgical method

Interventions

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Anwar

Anwar surgical method

Intervention Type PROCEDURE

Melles

Melles surgical method

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients with keratoconus
* 15\<age\<45
* contact lens intolerance

Exclusion Criteria

* Having a history of any other ophthalmic or systemic problem
* Central corneal scar
* descemet's membrane detachment
Minimum Eligible Age

15 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shahid Beheshti University of Medical Sciences

OTHER

Sponsor Role lead

Locations

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Ophtalmic Research Centre

Tehran, Tehran Province, Iran

Site Status

Farid Karimian,MD

Tehran, Tehran Province, Iran

Site Status

Countries

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Iran

Other Identifiers

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8721

Identifier Type: -

Identifier Source: org_study_id

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