Study Results
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Basic Information
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COMPLETED
PHASE3
40 participants
INTERVENTIONAL
2006-01-31
2008-12-31
Brief Summary
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Detailed Description
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Methods: Thirty four unselected consecutive patients were submitted to DALK big-bubble technique. Intraoperative and postoperative complications, postoperative uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), spherical equivalent (SE), corneal topography, and endothelial cell density were evaluated. All patients were followed for at least 6 months.
Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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1
Submitted to deep anterior lamellar keratoplasty (DALK) using the big-bubble technique.
Deep anterior lamellar keratoplasty (DALK)
Deep anterior lamellar keratoplasty (DALK) using the big-bubble technique.
2
Submitted to regular penetrating keratoplasty
Penetrated keratoplasty
Regular corneal transplant using the penetrated keratoplasty technique
Interventions
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Deep anterior lamellar keratoplasty (DALK)
Deep anterior lamellar keratoplasty (DALK) using the big-bubble technique.
Penetrated keratoplasty
Regular corneal transplant using the penetrated keratoplasty technique
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* glaucoma or intraocular pressure greater than 21 mmHg
* amblyopia
* retinal abnormalities
* diabetes mellitus
* steroid or immunosuppressive treatment
* connective tissue diseases
18 Years
ALL
No
Sponsors
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Hospital Oftalmologico de Brasilia
OTHER
Responsible Party
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HOB
Principal Investigators
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PATRICK F TZELIKIS, PhD, MD
Role: PRINCIPAL_INVESTIGATOR
Federal University of Minas Gerais
Locations
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Hospital Oftalmologico de BrasÃlia
BrasÃlia, Federal District, Brazil
Countries
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References
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Tan DT, Parthasarathy A. Deep anterior lamellar keratoplasty for keratoconus. Cornea. 2007 Sep;26(8):1025; author reply 1025-6. doi: 10.1097/ICO.0b013e31805771e3. No abstract available.
Vajpayee RB, Tyagi J, Sharma N, Kumar N, Jhanji V, Titiyal JS. Deep anterior lamellar keratoplasty by big-bubble technique for treatment corneal stromal opacities. Am J Ophthalmol. 2007 Jun;143(6):954-957. doi: 10.1016/j.ajo.2007.02.036. Epub 2007 Apr 16.
Ardjomand N, Hau S, McAlister JC, Bunce C, Galaretta D, Tuft SJ, Larkin DF. Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts. Am J Ophthalmol. 2007 Feb;143(2):228-235. doi: 10.1016/j.ajo.2006.10.043. Epub 2006 Nov 30.
Tzelikis PF, Santos JD, Garcez RC, Akaishi L. [Deep anterior lamellar keratoplasty by big-bubble technique]. Arq Bras Oftalmol. 2011 Nov-Dec;74(6):435-40. doi: 10.1590/s0004-27492011000600011. Portuguese.
Related Links
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Other Identifiers
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DALK
Identifier Type: -
Identifier Source: org_study_id
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