Deep Anterior Lamellar Keratoplasty (DALK) Using Acellular Corneal Tissue Promotes Corneal Allograft Survival in High Risk Patients
NCT ID: NCT01021046
Last Updated: 2010-08-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
78 participants
INTERVENTIONAL
2006-12-31
2010-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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GCCT,corneal allograft survival ,DALK
experimental group: deep anterior lamellar keratoplasty using glycerin-cryopreserved corneal tissue
DALK using GCCT
Deep anterior lamellar keratoplasty (DALK) using glycerin-cryopreserved corneal tissue
FCT,corneal allograft survival ,DALK
control group: deep anterior lamellar keratoplasty using fresh corneal tissue
DALK using FCT
Deep anterior lamellar keratoplasty (DALK) using fresh corneal tissue
Interventions
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DALK using GCCT
Deep anterior lamellar keratoplasty (DALK) using glycerin-cryopreserved corneal tissue
DALK using FCT
Deep anterior lamellar keratoplasty (DALK) using fresh corneal tissue
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Herpes simplex keratitis
* severe fungal keratitis
* partial limbal deficiency after chemical burn
Exclusion Criteria
* dry eye
* glaucoma or intraocular pressure greater than 21 mmHg
* amblyopia
* retinal abnormalities
* patients with severe systemic diseases not good for ocular surgery
18 Years
ALL
No
Sponsors
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Wenzhou Medical University
OTHER
Responsible Party
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Eye Hospital, Wenzhou Medical College
Principal Investigators
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Wei Chen, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Eye Hospital, Wenzhou Medical College, China
Locations
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Eye Hospital, Wenzhou Medical College
Wenzhou, Zhejiang, China
Countries
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References
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Li J, Yu L, Deng Z, Wang L, Sun L, Ma H, Chen W. Deep anterior lamellar keratoplasty using acellular corneal tissue for prevention of allograft rejection in high-risk corneas. Am J Ophthalmol. 2011 Nov;152(5):762-70.e3. doi: 10.1016/j.ajo.2011.05.002. Epub 2011 Jul 30.
Other Identifiers
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10001
Identifier Type: -
Identifier Source: org_study_id
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