Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-10-31

Brief Summary

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Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not demonstrated. Our hypothesis is that patients suffering from a more severe sleep apnea will demonstrate a greater degree of cognitive dysfunction.

Detailed Description

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Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of sleep disturbances and the degree of cognitive dysfunction was not demonstrated.We intend to study 80 patients with various degrees of obstructive sleep apnea. All patients will undergo executive cognitive tests as well as tests to assess for levels of depression, anxiety and attention.

Conditions

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Obstructive Sleep Apnea

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Apnea hypopnea index\>5
2. Age 20 - 70 years

Exclusion Criteria

1. Pregnant women
2. Known chronic cardiovascular or pulmonary disease
3. Patients s/p CVA or brain damage
4. Known depression or other psychiatric disorder
5. Patients with severe cognitive dysfunction (MMSE\<25)
6. Patients receiving stimulants, antipsychotic or anti-depression medications

Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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The Sleep Laboratory, Assaf Harofeh Medical Center, Zerifin, Israel

Other Identifiers

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143/06

Identifier Type: -

Identifier Source: org_study_id