Treatment of Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain

NCT ID: NCT00736346

Last Updated: 2008-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

204 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-10-31

Study Completion Date

2010-06-30

Brief Summary

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The purpose of this study is to assess the impact of three different treatment modalities on panic symptoms, quality of life and use of health services among individuals consulting an emergency department for non cardiac chest pain and having Panic Disorder.

Detailed Description

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Conditions

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Panic Disorder Anxiety Disorder Mental Disorder

Keywords

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Panic Disorder anxiety chest pain emergency department cognitive-behavioral treatment

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

Group Type ACTIVE_COMPARATOR

Brief cognitive-behavioral treatment for Panic Disorder

Intervention Type BEHAVIORAL

One two-hour session of cognitive-behavior therapy for panic disorder

2

Group Type ACTIVE_COMPARATOR

Cognitive-Behavior Therapy for Panic Disorder

Intervention Type BEHAVIORAL

Seven one-hour sessions of cognitive-behavior therapy for panic disorder

3

Group Type ACTIVE_COMPARATOR

paroxetine

Intervention Type DRUG

40 mg die, for 6 months

4

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Brief cognitive-behavioral treatment for Panic Disorder

One two-hour session of cognitive-behavior therapy for panic disorder

Intervention Type BEHAVIORAL

Cognitive-Behavior Therapy for Panic Disorder

Seven one-hour sessions of cognitive-behavior therapy for panic disorder

Intervention Type BEHAVIORAL

paroxetine

40 mg die, for 6 months

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Aged 18 and over
* Mastered oral and written French
* Consulted an emergency department for chest pain with very low risk of coronary disease (normal ECG and blood tests)
* Met criteria for Panic Disorder

Exclusion Criteria

* Chest pain with an obvious medical origin (obvious trauma or abnormal pulmonary x-rays)
* Had received cognitive-behavior therapy for Panic Disorder in the last six months
* Cognitive impairment preventing the completion of psychological assessment
* Past or present psychotic episode, Bipolar Disorder, or organic mental disorder
* Current Abuse or Dependence Disorder
* If another Mental Disorder is present, its severity was equal or inferior to the severity of Panic Disorder
* Current medical condition preventing the participant from receiving pharmacological of cognitive-behavior treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Canadian Institutes of Health Research (CIHR)

OTHER_GOV

Sponsor Role collaborator

Université du Québec a Montréal

OTHER

Sponsor Role lead

Responsible Party

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UQAM

Principal Investigators

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André Marchand, PhD

Role: PRINCIPAL_INVESTIGATOR

Université du Québec a Montréal

Locations

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Hôtel-Dieu de Lévis

Lévis, Quebec, Canada

Site Status RECRUITING

Institut de Cardiologie de Montréal (Montreal Heart Institute)

Montreal, Quebec, Canada

Site Status RECRUITING

Hôpital du Sacré-Coeur de Montréal

Montreal, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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André Marchand, PhD

Role: CONTACT

Phone: 1 (514) 987-3000

Email: [email protected]

Geneviève Belleville, PhD

Role: CONTACT

Email: [email protected]

Facility Contacts

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Julien Poitras, MD

Role: primary

Alain Vadeboncoeur, MD

Role: primary

Jean-Marc Chauny, MD

Role: primary

References

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Foldes-Busque G, Hamel S, Belleville G, Fleet R, Poitras J, Chauny JM, Vadeboncoeur A, Lavoie KL, Marchand A. Factors associated with pain level in non-cardiac chest pain patients with comorbid panic disorder. Biopsychosoc Med. 2016 Oct 18;10:30. doi: 10.1186/s13030-016-0081-5. eCollection 2016.

Reference Type DERIVED
PMID: 27777612 (View on PubMed)

Other Identifiers

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MOP 81128 (CIHR)

Identifier Type: -

Identifier Source: org_study_id