Internet-based Self-help Treatment for Panic Disorder: Two Ways of Complementary Psychological Support

NCT ID: NCT02402322

Last Updated: 2015-12-07

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

77 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-08-31

Study Completion Date

2014-11-30

Brief Summary

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The aim of this study was to compare two ways of administrating the complementary psychological support (scheduled vs. non-scheduled) in an online self-help program for panic disorder. In order to do so, the investigators studied: a) If there were differences in the intensity and frequency of the symptoms of panic disorder. b) If there were differences in the therapeutic adherence between the subjects receiving both kinds of complementary support. c) If the more time spent by a psychologist in therapeutic interventions produced the best results of therapeutic adherence / symptom improvement.

Seventy seven subjects followed the online self-help program for 8 weeks; 27 subjects had the support of a therapist via phone when they required it, 25 subjects had the support of a therapist weekly and 25 subjects were in the waiting list as a control group.

Detailed Description

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The aim of this study was to compare two ways of administrating the complementary psychological support (scheduled vs. non-scheduled) in an online self-help program for panic disorder. In order to do so, the investigators studied: a) If there were differences in the intensity and frequency of the symptoms of panic disorder. b) If there were differences in the therapeutic adherence between the subjects receiving both kinds of complementary support. c) If the more time spent by a psychologist in therapeutic interventions produced the best results of therapeutic adherence / symptom improvement.

Treatment program

Internet-based self-help program for anxiety disorders "FREE OF ANXIETY" was developed, based on cognitive behavioral therapy. The program is presented as an interactive course, which is divided into eight weekly modules.A number of therapeutic components are used: psychological education (modules 1-8), behavioral analysis (safety and avoidance behavior) (module 2), in vivo and interoceptive exposure (modules 2-8), relaxation training and diaphragmatic breathing (modules 1-4), cognitive restructuring (modules 4-5), mindfulness (Module 6) communication training (module 7), problem solving Module 8). The program also includes a messaging system between therapists and subjects.

Participants and Procedure

The participants were recruited using a google banner linked to searches about anxiety disorders. The individuals were redirected to a Web page which contained information about anxiety disorders and the aims of the study. Suicide risk (score of 3 in the 15th item of the Web Screening Questionnaire) was established as an exclusion criterion. The study was approved by the ethics committee of the Autonomous University of Barcelona.

Applicants completed the informed consent, the demographic questionnaire and a screening questionnaire online. One week later a psychologist who had been trained to apply the MINI International Neuropsychiatric Interview (Sheehan, Lecrubier, Harnett-Sheehan, Janavs,Weiller, Bonora, et al., 1997) assessed the presence of a current psychiatric diagnosis. Participants with Panic Disorder completed a battery of self-reported measures in order to assess panic disorder, anxiety, and depression symptoms.

After clinical evaluation, the participants were divided into three groups by a true random-number service.

The data collected were anonymized and coded

Seventy seven subjects followed the online self-help program for 8 weeks; 27 subjects had the support of a therapist via phone when they required it, 25 subjects had the support of a therapist weekly and 25 subjects were in the waiting list as a control group.

Participants completed self-reported measures at the end of the treatment, and six months later.

Statistical analyses

The investigators studied differences between participants with and without Panic Disorder regarding their gender and age, using Chi-square test and Student t-test.

The participants' pretreatment and posttreatment measures were analyzed with analysis of variance (ANOVA) with repeated measures. These were followed by t tests with Bonferroni-corrected p values. Effect sizes were calculated both within and between groups, and all calculations were based on the pooled standard deviation, Cohen's d.

All analyses were conducted using SPSS version 22 for Windows.

Conditions

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Panic Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Non-scheduled support

Participants received an Web-based cognitive behavioral treatment for Panic Disorder with the support of a therapist via phone when they required it.

Group Type ACTIVE_COMPARATOR

Non-scheduled support

Intervention Type BEHAVIORAL

Participants followed the online self-help program based on cognitive behavioral therapy for 8 weeks. They had the support of a therapist via phone when they required it.

Scheduled support

Participants received an Web-based cognitive behavioral treatment for Panic Disorder with the support of a therapist via phone weekly.

Group Type EXPERIMENTAL

Scheduled support

Intervention Type BEHAVIORAL

Participants followed the online self-help program based on cognitive behavioral therapy for 8 weeks. They had the support of a therapist via phone weekly.

Waiting list

Participants in a waiting list.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Scheduled support

Participants followed the online self-help program based on cognitive behavioral therapy for 8 weeks. They had the support of a therapist via phone weekly.

Intervention Type BEHAVIORAL

Non-scheduled support

Participants followed the online self-help program based on cognitive behavioral therapy for 8 weeks. They had the support of a therapist via phone when they required it.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Meet Diagnostic Statistical Manual criteria for panic disorder.
* Have suffered from panic disorder at least one year.
* Suffer from panic disorder as primary pathology.
* If the participant was taking medication for panic disorder / agoraphobia, the dose should be stable three months before the start of the program.

Exclusion Criteria

* Obtain a score of 26 or more on the Beck Depression Inventory II
* Suffer from another psychiatric illness that requires immediate attention.
* Risk of suicide, indicated by a score of 3 on the screening questionnaire.
* Being or having been in cognitive behavioral therapy .
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitat Autonoma de Barcelona

OTHER

Sponsor Role lead

Responsible Party

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Pablo Oromendia

PhD Candidate

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Beatriz Molinuevo, PhD

Role: STUDY_DIRECTOR

Department of Psychiatry and Forensic Medicine, Institute of Neurosciences, School of Medicine, Universitat Autònoma de Barcelona, Spain

Other Identifiers

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PTCCAP

Identifier Type: -

Identifier Source: org_study_id