Comparison of Psychotherapy Programs to Treat Panic Disorder
NCT ID: NCT00353470
Last Updated: 2022-12-23
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE3
201 participants
INTERVENTIONAL
2006-09-30
2012-09-30
Brief Summary
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Detailed Description
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Participants in this single blind study will be randomly assigned to receive PFPP, CBT, or ART for 12 weeks. All participants will attend between 19 and 24 treatment sessions over the course of the study. Upon completing the study, participants will attend monthly follow-up visits for an additional 12 months. Participants assigned to ART who have not responded by the end of treatment may opt to receive PFPP or CBT. Outcomes will be assessed using a variety of scales to determine depression and anxiety symptoms.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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1
Participants will receive panic focused psychodynamic psychotherapy for 12 weeks
Panic focused psychodynamic psychotherapy (PFPP)
PFPP will include 19 to 24 sessions over 12 weeks.
2
Participants will receive cognitive behavioral therapy-panic control treatment for 12 weeks
Cognitive behavioral therapy
CBT for panic disorder will include 19 to 24 sessions over 12 weeks.
3
Participants will receive applied relaxation training for 12 weeks
Applied relaxation training (ART)
ART with exposure protocol will include 19 to 24 sessions over 12 weeks.
Interventions
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Cognitive behavioral therapy
CBT for panic disorder will include 19 to 24 sessions over 12 weeks.
Applied relaxation training (ART)
ART with exposure protocol will include 19 to 24 sessions over 12 weeks.
Panic focused psychodynamic psychotherapy (PFPP)
PFPP will include 19 to 24 sessions over 12 weeks.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* History of at least one spontaneous panic attack per week within the month prior to study entry
Exclusion Criteria
* Lifetime history of any psychotic disorder, including bipolar disorder
* Acutely suicidal
18 Years
70 Years
ALL
No
Sponsors
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National Institute of Mental Health (NIMH)
NIH
Weill Medical College of Cornell University
OTHER
Responsible Party
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Principal Investigators
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Barbara Milrod, MD
Role: PRINCIPAL_INVESTIGATOR
Weill Medical College of Cornell University
Jacques P. Barber, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Pennsylvania
Locations
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Weill Medical College of Cornell University
New York, New York, United States
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania, United States
Countries
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References
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