Vestibular Dysfunction In Adult Patients With Panic Disorder With or Without Agoraphobia
NCT ID: NCT00004367
Last Updated: 2005-06-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
165 participants
INTERVENTIONAL
2000-05-31
Brief Summary
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II. Determine whether the prevalence of abnormalities on audiological tests of cochlear or brainstem function is elevated in panic disorder without agoraphobia or nonpanic anxiety disorder.
III. Determine whether symptom patterns can be identified that are indicative of vestibular abnormalities in panic disorder.
IV. Determine whether vestibular dysfunction can be induced by psychosomatic mechanisms.
Detailed Description
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Patients undergo a psychiatric interview and a structured interview focused on anxiety disorders. Physical evaluation is completed.
A vestibular evaluation consisting of posturography, rotational testing, and ocular motor screening battery, and positional and caloric testing is completed on all patients. Patients then complete an audiological test battery consisting of basic audiological analysis, speech recognition scores, immittance testing, brainstem evoked response, and determination of binaural masking level differences.
Control patients also complete a hyperventilation-rotational test.
Conditions
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Study Design
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DIAGNOSTIC
Interventions
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Clinical vestibular tests
Eligibility Criteria
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Inclusion Criteria
--Disease Characteristics-- Diagnostically proven panic disorders with or without moderate or severe agoraphobia and anxiety disorders without panic or agoraphobia Panic disorder may be accompanied by a secondary Axis 1 diagnosis of another disorder, such as depression, generalized anxiety disorder, or dependent, histrionic, or compulsive personality disorder --Prior/Concurrent Therapy-- Surgery: No prior ear surgery Other: No concurrent medication for medical or psychiatric conditions At least 2 weeks since prior medication No ototoxic drug intake --Patient Characteristics-- No medical disorders At least 2 weeks since prior upper respiratory tract infection and recovered No history of migraine No head trauma No scoliosis No alcoholism No drug abuse No family history of schizophrenia
18 Years
55 Years
ALL
Yes
Sponsors
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University of Pittsburgh
OTHER
National Center for Research Resources (NCRR)
NIH
Principal Investigators
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Rolf G. Jacob
Role: STUDY_CHAIR
University of Pittsburgh
Locations
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University of Pittsburgh
Pittsburgh, Pennsylvania, United States
Countries
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Other Identifiers
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UPITTS-9504279605
Identifier Type: -
Identifier Source: secondary_id
199/11945
Identifier Type: -
Identifier Source: org_study_id