Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features

NCT ID: NCT00665015

Last Updated: 2008-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2892 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-01-31

Study Completion Date

2006-10-31

Brief Summary

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Pleural effusion is a common complication of cardiac surgery. The aim of this study was to determine the prevalence, characteristics and determinants of clinically significant pleural effusions, defined as those requiring therapeutic pleural drainage.

Detailed Description

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This was a retrospective cohort study of prevalence and characteristics of patients who had a pleural effusion after coronary artery bypass graft, valve replacement or both procedures.

Information was collected on all consecutive patients who underwent CABG surgery and/or valve replacement between January 1, 2004 and December 31, 2005. Demographic information, anthropometric parameters, cardiac and renal function assessments, and comorbid conditions were retrieved from medical files. We also collected data on the type of procedure, whether it was elective or urgent, the number and origin of the grafts, the duration of surgery and of cardiopulmonary bypass and the postoperative complications, including pleural effusions. Clinical presentation and evolution of the effusions as well as pleural fluid characteristics were also studied.

Patients were considered to have a clinically significant pleural effusion when they met at least one of the following criteria: need for thoracentesis, a pleural drainage tube or a hospital readmission due to a pleural effusion that occurred within one year of surgery.

Conditions

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Pleural Effusion Coronary Artery Bypass

Keywords

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pleural effusion coronary artery bypass heart valve replacement

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Coronary artery bypass grafting (CABG)
* Valve replacement
* Combined CABG and valve replacement
* between January 1st, 2004 and December 31st, 2005

Exclusion Criteria

* Previous CABG
* Pulmonary and/or aortic artery surgery
* Heart or lung transplant
* Pleural effusion present at the time of surgery
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Laval University

OTHER

Sponsor Role lead

Responsible Party

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Unité de Recherche en Pneumologie, Hôpital Laval

Principal Investigators

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Louis-Philippe Boulet, MD, FRCP(C)

Role: PRINCIPAL_INVESTIGATOR

Unité de Recherche en Pneumologie, Hôpital Laval

Locations

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Unité de Recherche en Pneumologie, Hôpital Laval

Québec, Quebec, Canada

Site Status

Countries

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Canada

References

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Labidi M, Baillot R, Dionne B, Lacasse Y, Maltais F, Boulet LP. Pleural effusions following cardiac surgery: prevalence, risk factors, and clinical features. Chest. 2009 Dec;136(6):1604-1611. doi: 10.1378/chest.09-0689. Epub 2009 Jul 6.

Reference Type DERIVED
PMID: 19581352 (View on PubMed)

Other Identifiers

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PEFCS-summer 07

Identifier Type: -

Identifier Source: org_study_id