Effectiveness of a Femoral Block Following Total Knee Arthroplasty (TKA)

NCT ID: NCT00659087

Last Updated: 2016-08-03

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE4
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2008-04-30
• Study Completion Date: 2009-12-31

Brief Summary

Hospital stays after total joint replacement surgery have been getting shorter over the past 10 years. This is mostly due to new ways to manage pain and early rehabilitation. To be able to go home safely soon after surgery, patients need to:

• 1) have adequate pain control
• 2) be able to move through activities of daily living on their own (using aids)

Femoral nerve block, in combination with pain medications, is one of the new treatment strategies that are currently being used at other hospitals in Canada, the United States and the United Kingdom. Nerve blocks involve a needle filled with local anesthetic into the nerve that allows the feeling of pain around the knee. With good pain management, patients will be able to more quickly bend their knee and regain the ability to walk with aids and move from sitting and lying positions to standing and walking. Once they can do these activities with adequate pain control, they can be discharged from hospital to continue recovery at home. The purpose of this study is to examine a new way of managing postoperative pain and encourage early knee flexion and mobility, while maintaining pain control for patients after total knee replacement. We believe that patients who receive the nerve block in addition to the regular pain medication will have more knee flexion at discharge and experience less pain than patients who only receive usual pain medications.

Conditions

Total Knee Arthroplasty

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Femoral Block

Those receiving femoral block in addition to usual pain management

Group Type: EXPERIMENTAL

Femoral Block

Intervention Type: PROCEDURE

Those receiving femoral block postoperatively

Usual Care

Those receiving only usual pain management without a femoral block

Group Type: ACTIVE_COMPARATOR

Usual Care

Intervention Type: OTHER

Those receiving only usual pain management postoperatively

Interventions

Femoral Block

Those receiving femoral block postoperatively

Intervention Type: PROCEDURE

Usual Care

Those receiving only usual pain management postoperatively

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Undergoing primary total knee arthroplasty
• English-speaking
• Preoperative knee ROM > 90 degrees
• Body Mass Index < 40

Exclusion Criteria

• Regular preoperative opioid use
• Hepatic insufficiency
• Any contra-indications to receiving a femoral block

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Edmonton Civic Employees Research Fund

OTHER

Sponsor Role: lead

Responsible Party

Tsui, Ban / Johnston DWC

Pediatric and Adult Anesthesiologist, Associate Professor/Director of Clinical Research, Stollery Children's Hospital/University of Alberta Hospital

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

University of Alberta Hospitals

Edmonton, Alberta, Canada

Countries

Canada

Other Identifiers

J-3224

Identifier Type: -

Identifier Source: org_study_id