Functional Recovery After Total Knee Arthroplasty

NCT ID: NCT06821269

Last Updated: 2025-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-01

Study Completion Date

2027-05-01

Brief Summary

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The goal of this observational study is to learn about patients' recoveries after receiving total knee arthroplasty (TKA). The main questions it aims to answer are:

Does robotic-assisted TKA have improved perceived recovery when compared to conventional TKA? Does robotic-assisted TKA lead to improved functional recovery when compared to conventional TKA?

Researchers will compare if robotic-assisted versus conventional procedures lead to different recovery speeds.

Participants will answer questionnaires and undergo physical therapy testing before and at several timepoints after their procedure.

Detailed Description

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The choice to perform robotic assisted vs manual total knee arthroplasties (TKA) depends on many factors, including but not limited to surgeon training, resource availability, and patient-specific considerations. Recent studies comparing patient outcomes after robotic-assisted and manual total knee arthroplasties have shown mixed results. These studies often focus on future complication rates, radiographic outcomes, or patient reported outcomes between manual and robotic-assisted TKA. Hence, there has been little focus on improvements in functional outcomes after TKA. Combining functional test results, patient reported outcomes, kinematic studies, and data from wearable devices will allow for a comprehensive timeline of recovery speed after either robotic-assisted or manual TKA.

The overall aim of this proposed study is to quantify functional and PROM at specific timepoints in patients after robotic-assisted or manual total knee arthroplasty (TKA).

The questions are:

1. Do robotic-assisted revision TKAs have improved functional and perceived recovery when compared to manual revision TKAs?
2. Do robotic-assisted primary TKAs have improved functional and perceived recovery when compared to manual primary TKAs?
3. Do robotic-assisted revision TKAs have similar functional and perceived recovery as robotic-assisted primary TKAs?

For questions 1 and 2, we hypothesize that robotic-assisted revision or primary TKAs will have improved recovery when compared to manual TKAs.

For question 3, we hypothesize that robotic-assisted revision TKA will have similar recovery to primary robotic-assisted TKA.

Patients who are candidates for revision or primary TKA will be recruited within the Department of Orthopaedic Surgery. All subjects will participate in 6 evaluation sessions: anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery. Testing sessions will be approximately 1 hour long and will take place at the Physical Therapy Clinical and Translational Research Center (PT-CTRC).

At the time of enrollment, subjects will sign the informed consent in the presence of a study investigator. The research coordinator will collect data on demographics, medical history, and biomedical information. Note: Subjects who do not sign the consent form cannot participate in the study.

At each evaluation, patients will then be given time to complete the following patient reported outcome questionnaires: Forgotten Joint, Promis 29, Koos, SF 36. The physical therapist will then lead the patient through a series of functional measurement tests: Timed Up and Go (TUG), 4m and 10m walking speed test, sit/stand, Star Excursion Balance Test (SEBT), 2-minute walk, stair climb test (SCT), Single Leg Stance (SLS), and Y Balance Test (YBT). Videos may be taken to record progress.

Conditions

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Arthritis Knee

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Manual Revision TKA

These patients underwent revision TKA done manually

Manual revision total knee arthroplasty

Intervention Type PROCEDURE

Revision total knee arthroplasty without robotic assistance

Robotic-assisted Revision TKA

These patients underwent revision TKA with robotic-assistance

Robotic assisted revision total knee arthroplasty

Intervention Type PROCEDURE

Revision total knee arthroplasty with robotic assistance

Manual Primary TKA

These patients received primary TKAs done manually

Manual total knee arthroplasty

Intervention Type PROCEDURE

Total knee arthroplasty without robotic assistance

Robotic-assisted Primary TKA

These patients received primary TKAs with robotic-assistance

Robotic assisted total knee arthroplasty

Intervention Type PROCEDURE

Total knee arthroplasty with robotic assisatance

Interventions

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Manual total knee arthroplasty

Total knee arthroplasty without robotic assistance

Intervention Type PROCEDURE

Robotic assisted revision total knee arthroplasty

Revision total knee arthroplasty with robotic assistance

Intervention Type PROCEDURE

Manual revision total knee arthroplasty

Revision total knee arthroplasty without robotic assistance

Intervention Type PROCEDURE

Robotic assisted total knee arthroplasty

Total knee arthroplasty with robotic assisatance

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Candidate for TKA
* Speak English / understand study instructions--this is necessary to reliably complete the study questionnaires and understand study instructions which are not validated in other languages
* Have medical clearance from PCP, PI, or co-Investigator to participate in the study
* Willing to comply with all study procedures and be available for the duration of the study

Exclusion Criteria

* 2+ falls in the past year
* Unable to ambulate 100 ft without assistive device or rest period
* Acute illness
* Have a history of cardiovascular disease or hypertension not controlled by medication
* Severe visual impairment
* Lower-extremity amputation
* Neurological, muscular, systemic, or connective tissue disorder affecting the function of the lower extremities
* Pregnant
* Terminal illness
* Plans to have another joint replacement during study period
* Plans to relocate from immediate area during study period
Minimum Eligible Age

40 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Pittsburgh

OTHER

Sponsor Role lead

Responsible Party

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Kenneth Urish

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kenneth Urish, MD PhD

Role: PRINCIPAL_INVESTIGATOR

University of Pittsburgh

Locations

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University of Pittsburgh

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Victoria Wong, BA

Role: CONTACT

6503880143

Facility Contacts

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Kenneth Urish, MD, PhD

Role: primary

412-641-8609

Other Identifiers

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STUDY23060125

Identifier Type: -

Identifier Source: org_study_id

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