The Appropriate Level of Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty (TKA)

NCT ID: NCT04206150

Last Updated: 2021-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-02

Study Completion Date

2021-07-17

Brief Summary

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Adductor canal catheters are being used to provide continuous postoperative analgesia after total knee arthroplasty surgery (TKA). There is much debate about where is the best position of continuous adductor canal block in patients undergoing TKA. Therefore, the investigators aim to compare the postoperative pain at three different level of continuous adductor canal block. Ninety six patients scheduled for total knee arthroplasty will be randomly divided into the three groups. In group 1, the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal). In group 2, the adductor canal catheter is inserted femur length/15\*2 cm above the location where the nerve block performed in group 1. In group 3, the adductor canal catheter is inserted femur length/15cm below the location where the nerve block performed in group 1.

Detailed Description

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Conditions

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Degenerative Arthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Ninety six patients scheduled for total knee arthroplasty will be randomly divided into the three groups. In group 1, the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal). In group 2, the adductor canal catheter is inserted femur length/15\*2 cm above the location where the nerve block performed in group 1. In group 3, the adductor canal catheter is inserted femur length/15\*2 cm below the location where the nerve block performed in group 1.
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
Investigator and outcomes assessor are blinded to group assignment.

Study Groups

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Group 1(femoral triangle apex)

the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal)

Group Type ACTIVE_COMPARATOR

the three different sites of continous adductor canal block: the adductor canal catheter is inserted at femoral triangle apex

Intervention Type PROCEDURE

In group 1, the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal).

Group 2(femur length/15*2 cm above)

the adductor canal catheter is inserted femur length/15\*2 cm above the location where the nerve block performed in group 1

Group Type ACTIVE_COMPARATOR

the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15*2 cm above the location

Intervention Type PROCEDURE

In group 2, the adductor canal catheter is inserted femur length/15\*2 cm above the location where the nerve block performed in group 1.

Group 3(femur length/15 cm below)

the adductor canal catheter is inserted femur length/15cm below the location where the nerve block performed in group 1.

Group Type ACTIVE_COMPARATOR

the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15 cm below the location

Intervention Type PROCEDURE

In group 3, the adductor canal catheter is inserted femur length/15 cm below the location where the nerve block performed in group 1.

Interventions

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the three different sites of continous adductor canal block: the adductor canal catheter is inserted at femoral triangle apex

In group 1, the adductor canal catheter is inserted at femoral triangle apex (the proximal end of the adductor canal).

Intervention Type PROCEDURE

the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15*2 cm above the location

In group 2, the adductor canal catheter is inserted femur length/15\*2 cm above the location where the nerve block performed in group 1.

Intervention Type PROCEDURE

the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15 cm below the location

In group 3, the adductor canal catheter is inserted femur length/15 cm below the location where the nerve block performed in group 1.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* 1\. Patients undergoing total knee arthroplasty

Exclusion Criteria

* 1\. Patients who have infection or had surgery on the thigh
* 2\. The subject is a foreigner or illiterate
* 3\. Patients who have cognitive dysfunction
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Chuan A, Lansdown A, Brick KL, Bourgeois AJG, Pencheva LB, Hue B, Goddard S, Lennon MJ, Walters A, Auyong D; Continuous Catheters in Adductor Canal versus Femoral Triangle (The CAFE study) investigators. Adductor canal versus femoral triangle anatomical locations for continuous catheter analgesia after total knee arthroplasty: a multicentre randomised controlled study. Br J Anaesth. 2019 Sep;123(3):360-367. doi: 10.1016/j.bja.2019.03.021. Epub 2019 May 2.

Reference Type BACKGROUND
PMID: 31056239 (View on PubMed)

Sztain JF, Khatibi B, Monahan AM, Said ET, Abramson WB, Gabriel RA, Finneran JJ 4th, Bellars RH, Nguyen PL, Ball ST, Gonzales FB, Ahmed SS, Donohue MC, Padwal JA, Ilfeld BM. Proximal Versus Distal Continuous Adductor Canal Blocks: Does Varying Perineural Catheter Location Influence Analgesia? A Randomized, Subject-Masked, Controlled Clinical Trial. Anesth Analg. 2018 Jul;127(1):240-246. doi: 10.1213/ANE.0000000000003422.

Reference Type BACKGROUND
PMID: 29750695 (View on PubMed)

Lee B, Park SJ, Park KK, Kim HJ, Lee YS, Choi YS. Optimal location for continuous catheter analgesia among the femoral triangle, proximal, or distal adductor canal after total knee arthroplasty: a randomized double-blind controlled trial. Reg Anesth Pain Med. 2022 Jun;47(6):353-358. doi: 10.1136/rapm-2021-103284. Epub 2022 Feb 16.

Reference Type DERIVED
PMID: 35173020 (View on PubMed)

Other Identifiers

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4-2019-1038

Identifier Type: -

Identifier Source: org_study_id