Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

112 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-05-31

Study Completion Date

2009-01-31

Brief Summary

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This study aims to investigate neuroendocrine, autonomic functioning, and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

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Detailed Description

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The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-controled normal subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, basal metabolic rate measurement by indirect calorimetry, and ECG in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Conditions

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Anorexia Nervosa Bulimia Nervosa

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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1

No interventions assigned to this group

2

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa
* Normal controls

Exclusion Criteria

* Any major psychiatric disorders
* Use of psychoactive medications
* Drug and alcohol abuse
* Medical problems (cardiovascular condition and endocrine disorders)

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes