LACH-Trial: LAparoscopic Correction of Hernia

NCT ID: NCT00537927

Last Updated: 2009-02-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

215 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-08-31

Study Completion Date

2009-01-31

Brief Summary

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Method of fixation of the mesh in laparoscopic incisional / ventral hernia repair might influence the degree of postoperative pain.

The study hypothesis is that there is no difference in postoperative pain between different methods to fix the mesh in laparoscopic incisional / ventral hernia repair.

Detailed Description

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One of the complications in laparoscopic incisional / ventral hernia repair is postoperative pain. Method of fixation of the mesh in laparoscopic incisional / ventral hernia repair might influence the degree of this postoperative pain. Fixation of the mesh might also influence other outcome parameters such as return to preoperative activities, costs and recurrence rate.

The study hypothesis is that there is no difference in postoperative pain when comparing three commonly used mesh fixation techniques in laparoscopic incisional / ventral hernia repair.

Conditions

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Incisional Hernia Ventral Hernia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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0

fixation of mesh with a single crown of tacks and absorbable sutures

Group Type ACTIVE_COMPARATOR

laparoscopic correction of hernia with mesh

Intervention Type PROCEDURE

Correction of hernia with mesh and fixation of mesh using one of the arms.

1

fixation of mesh with a double crown of tacks and no sutures

Group Type ACTIVE_COMPARATOR

laparoscopic correction of hernia with mesh

Intervention Type PROCEDURE

Correction of hernia with mesh and fixation of mesh using one of the arms.

2

fixation of mesh with a single crown of tacks and non-absorbable sutures

Group Type ACTIVE_COMPARATOR

laparoscopic correction of hernia with mesh

Intervention Type PROCEDURE

Correction of hernia with mesh and fixation of mesh using one of the arms.

Interventions

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laparoscopic correction of hernia with mesh

Correction of hernia with mesh and fixation of mesh using one of the arms.

Intervention Type PROCEDURE

Other Intervention Names

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DualMesh Mersilene Vicryl ProTack Suture Passer

Eligibility Criteria

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Inclusion Criteria

* Non-acute incisional hernia of the abdominal wall or ventral hernia of the abdominal wall
* Informed consent
* Elective surgery

Exclusion Criteria

* \< 18 years and \> 80 years
* Prednison \> 15 mg/24hr, started more than 2 weeks prior to surgery
* Chronical cough (severe COPD etc)
* Ascites
* Peritoneal dialysis
* Current abdominal infection
* Complete loss of abdominal domain due to hernia (diameter more than 10 cm?)
* Re-laparoscopic correction of ventral hernia
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ziekenhuisgroep Twente

OTHER

Sponsor Role lead

Responsible Party

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Ziekenhuisgroep Twente

Principal Investigators

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Eelco B Wassenaar, MD

Role: PRINCIPAL_INVESTIGATOR

Ziekenhuisgroep Twente

Srjdan Rakic, MD, PhD

Role: STUDY_DIRECTOR

Ziekenhuisgroep Twente

Locations

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Ziekenhuisgroep Twente

Almelo, , Netherlands

Site Status

Countries

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Netherlands

References

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Goodney PP, Birkmeyer CM, Birkmeyer JD. Short-term outcomes of laparoscopic and open ventral hernia repair: a meta-analysis. Arch Surg. 2002 Oct;137(10):1161-5. doi: 10.1001/archsurg.137.10.1161.

Reference Type BACKGROUND
PMID: 12361426 (View on PubMed)

DeMaria EJ, Moss JM, Sugerman HJ. Laparoscopic intraperitoneal polytetrafluoroethylene (PTFE) prosthetic patch repair of ventral hernia. Prospective comparison to open prefascial polypropylene mesh repair. Surg Endosc. 2000 Apr;14(4):326-9. doi: 10.1007/s004640020013.

Reference Type BACKGROUND
PMID: 10790548 (View on PubMed)

LeBlanc KA. Laparoscopic incisional and ventral hernia repair: complications-how to avoid and handle. Hernia. 2004 Dec;8(4):323-31. doi: 10.1007/s10029-004-0250-5.

Reference Type BACKGROUND
PMID: 15235939 (View on PubMed)

Heniford BT, Park A, Ramshaw BJ, Voeller G. Laparoscopic repair of ventral hernias: nine years' experience with 850 consecutive hernias. Ann Surg. 2003 Sep;238(3):391-9; discussion 399-400. doi: 10.1097/01.sla.0000086662.49499.ab.

Reference Type BACKGROUND
PMID: 14501505 (View on PubMed)

Wassenaar E, Schoenmaeckers E, Raymakers J, van der Palen J, Rakic S. Mesh-fixation method and pain and quality of life after laparoscopic ventral or incisional hernia repair: a randomized trial of three fixation techniques. Surg Endosc. 2010 Jun;24(6):1296-302. doi: 10.1007/s00464-009-0763-1. Epub 2009 Dec 24.

Reference Type DERIVED
PMID: 20033726 (View on PubMed)

Other Identifiers

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P05-28

Identifier Type: -

Identifier Source: org_study_id

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