Open Lung Approach During General Anaesthesia to Prevent Post-Operative Pulmonary Complications
NCT ID: NCT00426790
Last Updated: 2007-01-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
INTERVENTIONAL
Brief Summary
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This is a prospective, randomized, controlled clinical-trial,performed in patients undergoing major abdominal surgery, to compare the effects on the post-operative pulmonary complications of two different intraoperative ventilatory strategies during general anaesthesia: 1- Control Group: PEEP 0 cmH2O without recruitment manoeuvre; 2- Treatment Group:recruitment manoeuvre (after intubation and before extubation) and PEEP 10 cmH2O In the post-operative period the following variables will be recorded at the first, third and fifth postoperative day: 1- Gas-exchange in air; 2- Chest X-ray for atelectasis evaluation; 3- signs of pulmonary complication (cough, secretions, dyspnea, thoracic pain)
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Interventions
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Positive end-expiratory pressure
Eligibility Criteria
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Inclusion Criteria
* Age higher than 18 years
* Major abdominal surgery
* General anesthesia
Exclusion Criteria
* Ischemic cardiopathy
* Loco-regional anesthesia alone
* Minor abdominal surgery
* Laparoscopic surgery
18 Years
ALL
No
Sponsors
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Università degli Studi dell'Insubria
OTHER
Principal Investigators
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Paolo Pelosi, Professor
Role: PRINCIPAL_INVESTIGATOR
University of Insubria, Varese, Italy
Locations
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Ospedale di Circolo e Fondazione Macchi
Varese, Varese, Italy
Countries
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Central Contacts
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Other Identifiers
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1400
Identifier Type: -
Identifier Source: org_study_id
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