Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-08

Study Completion Date

2025-12-19

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include ventilation and fluid measures

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Which Ventilatory Strategy is Better for Lung in Upper Abdominal Surgeries?

NCT04872361

Anesthesia Induced Atelectasis

UNKNOWN NA

Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure

NCT07186920

Postoperative Atelectasis Postoperative Pulmonary Atelectasis Postoperative Pulmonary Complications (PPCs) +2 more

COMPLETED NA

Effect of Ultrasound-assisted Lung Recruitment Maneuver on Preventing Perioperative Atelectasis

NCT06770179

Undergoing Surgery Perioperatif Atelectasis

ENROLLING_BY_INVITATION NA

Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound

NCT03069157

Anesthesia Induced Atelectasis

COMPLETED NA

The Effects of Pre-extubation Single Recruitment Maneuver on Perioperative Atelectasis

NCT05494255

Pulmonary Atelectasis

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

ultrasound evaluation for application of different preventive measures of post operative lung atelectasis, including positive end-expiratory pressure, lung recruitment maneuvers, and restrictive fluid management.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pulmonary Atelectasis, Postoperative

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The patients will be assigned into three equal groups of 20 patients each:

1. Group I: PEEP of 8 cm H2O and fluid management: 500 ml + 4 mL/kg/hour Ringer's lactate
2. Group II: PEEP/RM group, addition of RM (30 cm H2O for 30 s)
3. Group III: PEEP/RM group and restricted fluid management 3 mL/kg/hour Ringer's lactate

A total sample size of 60 patients will be involved.

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group I: PEEP

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Group Type EXPERIMENTAL

PEEP

Intervention Type OTHER

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Group II: PEEP/RM

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Group Type EXPERIMENTAL

PEEP/RM

Intervention Type OTHER

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Group III: PEEP/RM/RF

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Group Type EXPERIMENTAL

PEEP/RM/RF

Intervention Type OTHER

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PEEP

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Intervention Type OTHER

PEEP/RM

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Intervention Type OTHER

PEEP/RM/RF

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* ASA physical status I or II, of either gender.
* BMI \< 40
* Age 30-60 years
* scheduled for elective abdominal surgeries

Exclusion Criteria

* Patient refusal
* American Society of Anesthesiologists (ASA) physical status classification system more than II
* BMI \> 40 .
* Psychiatric disorders
* History of chest disorders such as asthma and obstructive pulmonary disease (COPD).
* History of Previous Thoracic Procedures.
* Pregnancy

Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No