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Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery

NCT ID: NCT06654778

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-08

Study Completion Date

2025-12-19

Brief Summary

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the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include ventilation and fluid measures

Detailed Description

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ultrasound evaluation for application of different preventive measures of post operative lung atelectasis, including positive end-expiratory pressure, lung recruitment maneuvers, and restrictive fluid management.

Conditions

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Pulmonary Atelectasis, Postoperative

Keywords

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lung ultrasound lung Atelectasis Atelectasis Pulmonary Atelectasis pressure controlled ventilation - volume guarantee (PCV- VG) positive end-expiratory pressure (PEEP) lung recruitment maneuver restrictive fluid strategies

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The patients will be assigned into three equal groups of 20 patients each:

1. Group I: PEEP of 8 cm H2O and fluid management: 500 ml + 4 mL/kg/hour Ringer's lactate
2. Group II: PEEP/RM group, addition of RM (30 cm H2O for 30 s)
3. Group III: PEEP/RM group and restricted fluid management 3 mL/kg/hour Ringer's lactate

A total sample size of 60 patients will be involved.
Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Group I: PEEP

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Group Type EXPERIMENTAL

PEEP

Intervention Type OTHER

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Group II: PEEP/RM

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Group Type EXPERIMENTAL

PEEP/RM

Intervention Type OTHER

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Group III: PEEP/RM/RF

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Group Type EXPERIMENTAL

PEEP/RM/RF

Intervention Type OTHER

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Interventions

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PEEP

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Intervention Type OTHER

PEEP/RM

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Intervention Type OTHER

PEEP/RM/RF

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ASA physical status I or II, of either gender.
* BMI \< 40
* Age 30-60 years
* scheduled for elective abdominal surgeries

Exclusion Criteria

* Patient refusal
* American Society of Anesthesiologists (ASA) physical status classification system more than II
* BMI \> 40 .
* Psychiatric disorders
* History of chest disorders such as asthma and obstructive pulmonary disease (COPD).
* History of Previous Thoracic Procedures.
* Pregnancy
Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Hamed Mohamed Wally Allah

Assistant lecturer in Anesthesia, Intensive Care and pain management department, Faculty of Medicine, Al-Azhar University (Assiut)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hamed M Wally Allah

Role: PRINCIPAL_INVESTIGATOR

Al-Azhar University

Locations

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Al-Azhar university

Asyut, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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AZAST/MD/209/MARCH/2024

Identifier Type: -

Identifier Source: org_study_id