Periapical Bone Healing After Apicectomy With and Without Retrograde Root Filling

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1/PHASE2

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-01-31

Study Completion Date

2008-09-30

Brief Summary

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Ph.D project: Periapical bone healing after apicectomy with and without retrograde root filling.

The aim of this study is to assess periapical bone healing after apicectomy without a filling and apicectomy combined with a retrograde filling material, MTA. Further, we will estimate risk factors in non-healing cases.

Study hypothesis: There is no difference in treatment outcome between:

Periapical bone healing after apicectomy with retrograde root filling and Periapical bone healing after apicectomy without retrograde root filling

Detailed Description

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Ph.D project: Periapical bone healing after apicectomy with and without retrograde root filling.

60 patients have been selected from a group of 490 patients, who had a full mouth radiographic status taken in connection with a population study of apical periodontitis in Aarhus Community. The selection criteria for the 60 patients were patients with a persisting apical periodontitis, Periapical Index (PAI) score 3-5, on front teeth and premolars in the upper jaw. The orthograde root filling in the tooth must be at least 2 years old and sufficient regarding density and length.

The 60 patients will be randomised into the two groups of apicectomy with and without filling. A radiograph will be taken just before the operation and 6 and 12 months after the operation. In the assessment of bone healing, we will use two different techniques, subtraction radiography and the Periapical Index (PAI).

We will also evaluate the benefits of using the operation microscope during the operation, and if clinical photos can be useful as documentation of treatment result.

Conditions

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Stomatognathic Disease Mouth Disease Periapical Disease Alveolar Bone Loss

Keywords

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Apicoectomy Retrograde MTA

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Mineral Trioxide Aggregate (MTA)

retrograde rootfilling with MTA or smoothening of the orthograde root-filling, gutta-percha

Intervention Type PROCEDURE

Other Intervention Names

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retrograde root filling material retrofilling

Eligibility Criteria

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Inclusion Criteria

healthy person age 18 or above sufficient root filling sufficient coronal restauration apical infection for at least 2 years Pai Score3, 4, or 5

Exclusion Criteria

boneless more than 50 % communication between pocket and apical infection no visible root filling material after apicectomy facial bone less than 3 mm

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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department of Oral Radiology, School of Dentistry, University of Aarhus, Denmark

Principal Investigators

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Ann Wenzel, professor

Role: STUDY_DIRECTOR

faculty of health science, royal dental collegue, department of Oral Radiology, Aarhus

Locations

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Faculty of Health Science

Aarhus, Aarhus C, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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journal n. 20050041

Identifier Type: -

Identifier Source: org_study_id