Three Dimensional Evaluation of Apexogenesis of Immature Young Permanent Teeth With Different Endodontic Material

NCT ID: NCT05790629

Last Updated: 2023-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-08

Study Completion Date

2024-05-31

Brief Summary

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Randomized Clinical Trial using Three Dimensional Evaluation of Apexogensis of immature young permanent teeth with Different Endodontic Tri-calcium Silicate-Based Putties

Detailed Description

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Treatment of immature permanent teeth has always been challenging in endodontics, not only because of their wide-open root apices but also because of the thin underdeveloped dentinal walls.Apexogenesis falls under the category of vital pulp therapy (VPT) procedure to maintain pulp vitality, induce dentin bridge formation and encourage continued root maturation.

To overcome the drawbacks of tricalcium silicate-based cements, a range of bioactive endodontic cements have been developed.

EndoSequence BC RRM-Fast Set Putty and NeoPutty (NuSmile, Houston, TX, USA) are the two materials evaluated in this study.

Conditions

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Deep Carious Young 1st Permanent Molar With Open Apex

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
children do not know which material used

Study Groups

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Group (I) control

young permanent pulpy exposed carious tooth of the selected participants will be treated with specific technique called apexogenesis using bio-compatible material (endo-sequence putty ). This material is administrated to the tooth by placing about 2-4 mm bulk of material in the pulp champers at the cervical line then sealing the capping material with glass ionomer and stainless steel crown.

Group Type ACTIVE_COMPARATOR

endo-sequence putty

Intervention Type PROCEDURE

pupal medicament which is materials used in case of vital pulp therapy (VPT) procedure after opening access in the inflamed pulp to maintain it is vitality, inducing dentin bridge formation and encourage continued root maturation.

Group (II)

young permanent pulpy exposed carious tooth of the selected participants will be treated with specific technique called apexogenesis using bio-compatible material (neo-MTA putty). This material is administrated to the tooth by placing about 2-4 mm bulk of material in the pulp champers at the cervical line then sealing the capping material with glass ionomer and stainless steel crown.

Group Type EXPERIMENTAL

neo-MTA putty

Intervention Type PROCEDURE

pupal medicament which is materials used in case of vital pulp therapy (VPT) procedure after opening access in the inflamed pulp to maintain it is vitality, inducing dentin bridge formation and encourage continued root maturation.

Interventions

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endo-sequence putty

pupal medicament which is materials used in case of vital pulp therapy (VPT) procedure after opening access in the inflamed pulp to maintain it is vitality, inducing dentin bridge formation and encourage continued root maturation.

Intervention Type PROCEDURE

neo-MTA putty

pupal medicament which is materials used in case of vital pulp therapy (VPT) procedure after opening access in the inflamed pulp to maintain it is vitality, inducing dentin bridge formation and encourage continued root maturation.

Intervention Type PROCEDURE

Other Intervention Names

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Endodontic Tri-calcium Silicate-Based Puty Endodontic Tri-calcium Silicate-Based Puty

Eligibility Criteria

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Inclusion Criteria

* First permanent molar with pulpitis.
* Sufficient tooth structure for placing rubber dam.
* Presence of open apex.
* Short root length.

Exclusion Criteria

* Insufficient tooth structure that need post and core.
* Presence of swelling.
* Presence of sinus tract.
* Presence of root fracture.
* Presence of root crack.
* Presence of external or internal root resorption.
* Presence of periapical pathosis.
* Presence of root calcification.
Minimum Eligible Age

6 Years

Maximum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Alaa M Eldehna

lecturer of Pediatric dentistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al-Azhar university dental clinics and 6 October university dental clinics

Cairo, Choose A State Or Province, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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alaa M mohammed, Ph. D

Role: CONTACT

+201068837641

Facility Contacts

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alaa mohammed

Role: primary

01068837641

Other Identifiers

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P-PD-22-26

Identifier Type: -

Identifier Source: org_study_id

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