Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

NCT ID: NCT00000261

Last Updated: 2015-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

1997-11-30

Study Completion Date

1998-10-31

Brief Summary

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The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers. All subjects underwent psychomotor testing during 4 sessions of placebo, drug/placebo, and choice of intervention.

Detailed Description

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Conditions

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Alcohol-Related Disorders Opioid-Related Disorders Substance-Related Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Moderate drinking adults

Group Type EXPERIMENTAL

30% Nitrous oxide

Intervention Type DRUG

Placebo

Intervention Type OTHER

No drug (100% oxygen)

0.2% sevoflurane

Intervention Type DRUG

0.4% sevoflurane

Intervention Type DRUG

0.6% sevoflurane

Intervention Type DRUG

Interventions

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30% Nitrous oxide

Intervention Type DRUG

Placebo

No drug (100% oxygen)

Intervention Type OTHER

0.2% sevoflurane

Intervention Type DRUG

0.4% sevoflurane

Intervention Type DRUG

0.6% sevoflurane

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

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Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

University of Chicago

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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James Zacny, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Chicago

Locations

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University of Chicago, Anesthesia & Critical Care

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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R01DA008391

Identifier Type: NIH

Identifier Source: secondary_id

View Link

R01-08391-13

Identifier Type: -

Identifier Source: secondary_id

NIDA-08391-13

Identifier Type: -

Identifier Source: org_study_id

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