Clinical Trials Updated in 2025

NCT03291067 | COMPLETED | PHASE2

375 Participants

MT-8554 for Reduction of Vasomotor Symptoms in Postmenopausal Women

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-10-09

Completion: 2018-10-19

Conditions

Menopause Hot Flashes

Interventions

DRUG

Results Available

NCT03203330 | ACTIVE_NOT_RECRUITING | PHASE3

535 Participants

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2018-10-30

Completion: 2024-07-10

Conditions

Degenerative Osteoarthritis

Interventions

BIOLOGICAL

No Results Yet

NCT03199885 | COMPLETED | PHASE3

190 Participants

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2019-04-05

Completion: 2024-04-30

Conditions

Metastatic Breast Adenocarcinoma Metastatic HER2-Positive Breast Carcinoma Recurrent Breast Adenocarcinoma Recurrent HER2-Positive Breast Carcinoma Stage III Breast Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7 Unresectable Breast Carcinoma Unresectable HER2-Positive Breast Carcinoma

Interventions

DRUG PROCEDURE BIOLOGICAL OTHER

Results Available

NCT03192891 | COMPLETED

2349 Participants

Stress CMR Perfusion Imaging in the United States (SPINS) Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2016-12-01

Completion: 2019-11-30

Conditions

Myocardial Ischemia

Interventions

DIAGNOSTIC_TEST

Results Available

NCT03115333 | ACTIVE_NOT_RECRUITING | NA

146 Participants

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-07-25

Completion: 2025-12-31

Conditions

Gliosarcoma Recurrent Glioblastoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03072927 | RECRUITING

8000 Participants

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2017-03-10

Completion: 2026-12-31

Conditions

Lumbar Spinal Stenosis

Interventions

DEVICE

No Results Yet

NCT03036930 | ACTIVE_NOT_RECRUITING | PHASE2

51 Participants

Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-06-23

Completion: 2024-03-04

Conditions

Human Papillomavirus Infection Human Papillomavirus-Related Carcinoma

Interventions

PROCEDURE OTHER BIOLOGICAL

Results Available

NCT02990286 | COMPLETED | PHASE3

122 Participants

Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung Diseases

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-01-20

Completion: 2019-07-24

Conditions

Lung Disease, Interstitial

Interventions

DRUG

No Results Yet

NCT02975310 | RECRUITING | NA

140 Participants

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-04-11

Completion: 2025-12-31

Conditions

Sinusitis Nasal Polyps

Interventions

PROCEDURE OTHER

No Results Yet

NCT02917473 | COMPLETED | NA

420 Participants

Comparison of Two Strategies for Counseling Skin Examination and Sun Protection in First-degree Relatives of Patients With Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-12-13

Completion: 2019-04-26

Conditions

Melanoma Screening

Interventions

BEHAVIORAL

No Results Yet

NCT02860000 | ACTIVE_NOT_RECRUITING | PHASE2

96 Participants

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2017-07-06

Completion: 2022-01-10

Conditions

Estrogen Receptor Status HER2/Neu Negative Invasive Breast Carcinoma Postmenopausal Stage III Breast Cancer Stage IIIA Breast Cancer Stage IIIB Breast Cancer Stage IIIC Breast Cancer Stage IV Breast Cancer

Interventions

DRUG OTHER

Results Available

NCT02837237 | COMPLETED | PHASE1

11 Participants

Safety, Tolerability, and Pharmacokinetics of KBP-5074 Following Oral Administration in Chronic Kidney Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2016-07-13

Completion: 2016-12-20

Conditions

Chronic Kidney Disease

Interventions

DRUG

Results Available

NCT02789839 | COMPLETED | NA

102 Participants

Analyses of Bone Marrow and Blood Samples From Healthy Volunteers: Focus on the redOx Metabolism

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2016-08-31

Completion: 2017-08-31

Conditions

redOx Metabolism

Interventions

PROCEDURE

No Results Yet

NCT02730039 | ACTIVE_NOT_RECRUITING

350 Participants

Meaning-Centered Psychotherapy Training for Cancer Care Providers

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2015-12-11

Completion: 2026-12-11

Conditions

Cancer Care Providers

Interventions

BEHAVIORAL

No Results Yet

NCT02727972 | COMPLETED | NA

180 Participants

Examination of Glutamate and mGluR5 in Psychiatric Disorders

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2012-02-21

Completion: 2022-01-13

Conditions

Major Depressive Disorder Post-Traumatic Stress Disorder Bipolar Disorder

Interventions

BEHAVIORAL OTHER RADIATION

No Results Yet

NCT02664545 | ACTIVE_NOT_RECRUITING | NA

100 Participants

Bridge-Enhanced ACL Repair vs ACL Reconstruction

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2016-04-30

Completion: 2019-06-19

Conditions

Anterior Cruciate Ligament Tear

Interventions

DEVICE PROCEDURE

Results Available

NCT02570620 | COMPLETED | NA

342 Participants

Contribution of Ultrasonography in the Evaluation of Cervical Induction-delivery Time

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2010-09-30

Completion: 2014-03-31

Conditions

Delivery Uterine Birth; Induced

Interventions

DEVICE

No Results Yet

NCT02533206 | ACTIVE_NOT_RECRUITING | NA

20 Participants

Pilot Study of The EPIC Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2015-08-31

Completion: 2022-12-31

Conditions

Sinusitis Nasal Polyps

Interventions

PROCEDURE

No Results Yet

NCT02455284 | COMPLETED | NA

134 Participants

In Vivo and ex Vivo Validation of MR Tractography of Brain White Matter Tracts - FIBRATLAS II-III

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2015-10-31

Completion: 2021-02-28

Conditions

Neurological Diseases

Interventions

DEVICE

No Results Yet

NCT02285192 | ACTIVE_NOT_RECRUITING | PHASE1

42 Participants

Positron Lymphography Via Intracervical 18F-FDG Injection for Pre-surgical Lymphatic Mapping in Stage IB1 Cervical Cancer and High-grade Endometrial Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2014-11-30

Completion: 2026-11-30

Conditions

Cervical Cancer Endometrial Cancer

Interventions

RADIATION DEVICE

No Results Yet

NCT02276885 | ACTIVE_NOT_RECRUITING | NA

284 Participants

Prone Partial Breast Irradiation (PBI): a Prospective Randomized Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2014-10-28

Completion: 2023-12-07

Conditions

Breast Cancer

Interventions

RADIATION

Results Available

NCT02270814 | ACTIVE_NOT_RECRUITING | PHASE2

74 Participants

Cisplatin, Nab-Paclitaxel, and Cetuximab (CACTUX) in Patients With Incurable Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2015-02-02

Completion: 2026-06-30

Conditions

Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Cancer of the Head and Neck

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT02229123 | COMPLETED | PHASE2

18 Participants

Levetiracetam Treatment of Neonatal Seizures: Safety and Efficacy Phase II Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2018-02-27

Completion: 2022-02-23

Conditions

Neonatal Seizures

Interventions

DRUG

No Results Yet

NCT02131805 | COMPLETED | NA

36 Participants

Electronic Skin Surface Brachytherapy for Cutaneous Basal Cell and Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2014-05-31

Completion: 2025-12-23

Conditions

Cutaneous Basal Cell Squamous Cell Carcinoma

Interventions

RADIATION BEHAVIORAL

No Results Yet

NCT02122107 | ACTIVE_NOT_RECRUITING

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2012-11-20

Completion: 2026-10-31

Conditions

Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases

No Results Yet

NCT00565851 | ACTIVE_NOT_RECRUITING | PHASE3

1052 Participants

Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2007-12-06

Completion: 2019-04-30

Conditions

Clear Cell Adenocarcinoma Fallopian Tube Clear Cell Adenocarcinoma Fallopian Tube Endometrioid Adenocarcinoma Fallopian Tube Mucinous Adenocarcinoma Fallopian Tube Serous Adenocarcinoma Fallopian Tube Transitional Cell Carcinoma Fallopian Tube Undifferentiated Carcinoma Mucinous Adenocarcinoma Ovarian Brenner Tumor Ovarian Clear Cell Adenocarcinofibroma Ovarian Clear Cell Adenocarcinoma Ovarian Endometrioid Adenocarcinoma Ovarian Seromucinous Carcinoma Ovarian Serous Adenocarcinoma Ovarian Transitional Cell Carcinoma Ovarian Undifferentiated Carcinoma Primary Peritoneal Clear Cell Adenocarcinoma Primary Peritoneal Endometrioid Adenocarcinoma Primary Peritoneal Serous Adenocarcinoma Primary Peritoneal Transitional Cell Carcinoma Primary Peritoneal Undifferentiated Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Undifferentiated Carcinoma

Interventions

BIOLOGICAL DRUG OTHER

Results Available

NCT00515060 | RECRUITING

450 Participants

Psychophysical Studies of Cancer Therapy Pain

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2001-01-23

Completion: 2028-04-30

Conditions

Advanced Cancer Pain

Interventions

OTHER

No Results Yet

NCT00465712 | TERMINATED | NA

119 Participants

Effect of Amnioinfusion on External Cephalic Version Successful Rate

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2006-07-31

Completion: 2011-05-31

Conditions

Breech Presentation

Interventions

PROCEDURE

No Results Yet

NCT00255346 | COMPLETED | PHASE2

68 Participants

Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2005-11-15

Completion: 2017-03-03

Conditions

Acute Myeloid Leukemia Myelodysplastic Syndromes Agnogenic Myeloid Metaplasia Myelofibrosis Hypereosinophilic Syndrome Polycythemia Vera Mastocytosis Leukemia, Myelomonocytic, Chronic

Interventions

DRUG

Results Available

NCT00177268 | RECRUITING

200 Participants

Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2004-10-31

Completion: 2030-01-31

Conditions

Cutaneous T-cell Lymphoma Sezary Syndrome Mycosis Fungoides Eczema Atopic Dermatitis

Interventions

OTHER

No Results Yet

NCT00006436 | COMPLETED | PHASE2

68 Participants

EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2001-01-29

Completion: 2020-11-30

Conditions

Lymphoma, AIDS-related Lymphoma, Large B-Cell, Diffuse

Interventions

BIOLOGICAL DRUG

Results Available

NCT07308626 | COMPLETED | NA

15 Participants

Acute Effects of Reformer, Cadillac, and Chair Pilates Appa-ratuses on Cardiac Autonomic Modulation and Flexibility

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-07-25

Completion: 2025-09-25

Conditions

Pilates Exercise Healhty Exercise Response

Interventions

BEHAVIORAL

No Results Yet

NCT07308587 | NOT_YET_RECRUITING

100 Participants

Evaluation of Intercostal Neuralgia in Patients With Chest Tube Insertion After Traumatic Rib Fracture

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2026-01-01

Completion: 2026-12-31

Conditions

Intercostal Nerve Injury

Interventions

PROCEDURE

No Results Yet

NCT07308574 | NOT_YET_RECRUITING | PHASE4

20 Participants

Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS

Study Type: INTERVENTIONAL

Last Updated: 2025-12-29

Start Date: 2025-12-26

Completion: 2027-06-25

Conditions

aHUS Atypical Hemolytic Uremic Syndrome

Interventions

DRUG

No Results Yet

NCT07308561 | RECRUITING

191 Participants

The Relationship Between Quality of Life, Anxiety Levels, and Attitudes Toward Artificial Intelligence Among Women Undergoing Infertility Treatment

Study Type: OBSERVATIONAL

Last Updated: 2025-12-29

Start Date: 2025-10-23

Completion: 2026-10-23

Conditions

Infertility, Female Artificial Intelligence Quality of Life Anxiety

No Results Yet