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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06828380 | RECRUITING | PHASE2
128 Participants

A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-15
Completion: 2028-08-06
Conditions
Advanced Hepatocellular Carcinoma (HCC)
Interventions
RADIATION
No Results Yet
NCT06828263 | RECRUITING
130 Participants

Prospective Evaluation of Imaging Response Biomarkers During [177Lu]Lu-PSMA in Metastatic Castration-resistant Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-01
Completion: 2043-06-30
Conditions
Prostate Cancer Metastatic Disease
No Results Yet
NCT06823271 | RECRUITING | NA
20 Participants

Haemodynamics and Ventricular Arrhythmias During Exercise in Patients With Arrhythmogenic Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-01
Completion: 2026-06-30
Conditions
Arrhythmias, Cardiac
Interventions
OTHER
No Results Yet
NCT06817889 | RECRUITING | PHASE2
60 Participants

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-23
Completion: 2027-11-30
Conditions
Hematopoietic and Lymphatic System Neoplasm Autoimmune Disease Respiratory Syncytial Virus Infection
Interventions
DRUG OTHER PROCEDURE
No Results Yet
NCT06816524 | NOT_YET_RECRUITING | NA
324 Participants

The Effects of Iron Treatment on Malaria and Measles Vaccine Response in Kenyan Infants With Iron Deficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-05
Completion: 2027-12-31
Conditions
Iron Deficiencies
Interventions
DIETARY_SUPPLEMENT BIOLOGICAL
No Results Yet
NCT06803875 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-01-31
Completion: 2027-12-31
Conditions
Relapsed Neuroblastoma Refractory Neuroblastoma High-risk Neuroblastoma
Interventions
BIOLOGICAL
No Results Yet
NCT06801015 | ACTIVE_NOT_RECRUITING | PHASE4
30 Participants

Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-01
Completion: 2028-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06789445 | RECRUITING | PHASE1/PHASE2
54 Participants

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-10
Completion: 2029-10-31
Conditions
Primary Photoreceptor Disease Retinitis Pigmentosa (RP) Usher Syndrome Cone-Rod Dystrophy Inherited Retinal Disease (IRD) Rod-Cone Dystrophy Rod-Cone Disease Cone-Rod Disease Retinal Degeneration
Interventions
BIOLOGICAL
No Results Yet
NCT06774924 | RECRUITING | NA
100 Participants

"Clinical Ultrasound, a New Link Between Town and Hospital in Seine-Saint-Denis". (ECHO93)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-12
Completion: 2026-09-30
Conditions
Diagnosis Clinical Ultrasound
Interventions
DEVICE
No Results Yet
NCT06773104 | COMPLETED | NA
24 Participants

Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-03-25
Completion: 2025-01-16
Conditions
Immediate Dental Implants Thin Labial Plate of Bone Pre-extraction Hopeless Tooth in Esthetic Zone
Interventions
PROCEDURE
No Results Yet
NCT06764706 | RECRUITING
200 Participants

Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-27
Completion: 2028-07-31
Conditions
Ulcerative Colitis
No Results Yet
NCT06752941 | RECRUITING
36 Participants

LOW-PV Continuation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-30
Completion: 2026-03-30
Conditions
Polycythemia Vera
No Results Yet
NCT06748092 | RECRUITING | NA
250 Participants

Clinical Validation of iCare IC1000 Tonometer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-21
Completion: 2026-02-28
Conditions
Intraocular Pressure
Interventions
DEVICE
No Results Yet
NCT06745076 | RECRUITING | PHASE2
125 Participants

Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-06
Completion: 2032-01-03
Conditions
Advanced Hodgkin Lymphoma Classic Hodgkin Lymphoma Lugano Classification Stage III Hodgkin Lymphoma AJCC v8 Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06744218 | RECRUITING | NA
46 Participants

Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthroscopic Rotator Cuff Repair Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-22
Completion: 2026-10-31
Conditions
Rotator Cuff Injuries
Interventions
PROCEDURE
No Results Yet
NCT06736106 | RECRUITING | NA
200 Participants

Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery?

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-01
Completion: 2026-08-31
Conditions
Spine Injuries and Disorders
Interventions
OTHER
No Results Yet
NCT06727604 | RECRUITING | PHASE2
240 Participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-17
Completion: 2028-06-30
Conditions
Graves' Disease
Interventions
DRUG
No Results Yet
NCT06726629 | RECRUITING
200 Participants

Crosscultural Adaptation And Validation Of The Italian Version Of The New Knee Society Knee Scoring System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-01
Completion: 2026-11-30
Conditions
Knee Osteoarthritis
Interventions
OTHER
No Results Yet
NCT06717477 | ENROLLING_BY_INVITATION
200 Participants

Streamlining Care for Patients With Compression Neuropathies: The Carpal Tunnel Plus Pathway

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-18
Completion: 2026-03-31
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
PROCEDURE
No Results Yet
NCT06714253 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-05
Completion: 2027-08-31
Conditions
Radiation-Induced Xerostomia and Hyposalivation
Interventions
BIOLOGICAL
No Results Yet
NCT06695325 | RECRUITING
300 Participants

Convenient Home Access for Routine Monitoring in Diabetes (Charm-D Study)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-04
Completion: 2026-07-01
Conditions
Diabetes Mellitus
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06680817 | RECRUITING
850 Participants

A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-05
Completion: 2027-06-30
Conditions
Neovascular Age-related Macular Degeneration Diabetic Macular Edema
Interventions
DRUG
No Results Yet
NCT06675032 | ACTIVE_NOT_RECRUITING | PHASE1
230 Participants

Phase I Clinical Trial of PCV24 in Children Aged 2 Months (Minimum 6 Weeks) to 17 Years

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-04-27
Completion: 2025-05-10
Conditions
Pneumococcal Infectious Disease
Interventions
BIOLOGICAL
No Results Yet
NCT06671392 | ACTIVE_NOT_RECRUITING | PHASE3
192 Participants

A Phase III Study to Efficacy and Safety of DWC202405/DWC202313 and DWC202314 in Patients With Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-24
Completion: 2026-02-28
Conditions
Essential Hypertension
Interventions
DRUG
No Results Yet
NCT06665308 | COMPLETED
81 Participants

Cognitive Status, Fatigue and Inflammation in Patients With Immune Thrombocytopenia (ITP)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-01-13
Completion: 2025-11-26
Conditions
Chronic Immune Thrombocytopenia Primary Immune Thrombocytopenia Adult Immune Thrombocytopenia
Interventions
OTHER
No Results Yet
NCT06659666 | COMPLETED
100 Participants

The COPD Optimiser

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-09
Completion: 2025-01-20
Conditions
COPD
Interventions
DEVICE
No Results Yet
NCT06656819 | RECRUITING
50 Participants

The Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2020-07-01
Completion: 2025-12-31
Conditions
Healthy
Interventions
DEVICE
No Results Yet
NCT06654778 | COMPLETED | NA
60 Participants

Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-08
Completion: 2025-12-19
Conditions
Pulmonary Atelectasis, Postoperative
Interventions
OTHER
No Results Yet
NCT06651281 | RECRUITING | PHASE3
1380 Participants

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-25
Completion: 2037-12-17
Conditions
Crohn Disease Colitis, Ulcerative
Interventions
DRUG
No Results Yet
NCT06650995 | RECRUITING | NA
40 Participants

AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-02-01
Completion: 2027-02-25
Conditions
HFpEF - Heart Failure With Preserved Ejection Fraction Atrial Fibrillation
Interventions
OTHER
No Results Yet
NCT06646016 | WITHDRAWN | PHASE2
0 Participants

EPIC- Extracorporeal Photopheresis (ECP) for Immune-related Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-15
Completion: 2026-02-06
Conditions
Immune-related Colitis
Interventions
DRUG
No Results Yet
NCT06633250 | RECRUITING | NA
104 Participants

Effect of a Hydrolyzed Rice Protein-based Formula on Growth, Tolerance, and Health-related Quality of Life in Infants With Cow's Milk Protein Allergy.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-25
Completion: 2026-08-31
Conditions
Cow Milk Protein Allergy
Interventions
OTHER
No Results Yet
NCT06625177 | RECRUITING | PHASE1
36 Participants

A Trial to Test the Safety and Efficacy of TEV-53408 in Treating Vitiligo

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-11
Completion: 2026-05-09
Conditions
Vitiligo
Interventions
DRUG
No Results Yet
NCT06625112 | RECRUITING
120 Participants

A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-04
Completion: 2029-10-31
Conditions
STXBP1 Encephalopathy With Epilepsy
No Results Yet
NCT06614725 | COMPLETED | PHASE3
751 Participants

A Study in India on the Immune Response and Safety of a Respiratory Syncytial Virus (RSV) Older Adults (OA) Vaccine When Given to Older Adults 60 Years of Age and Above and Adults 50-59 Years of Age at Increased Risk (AIR) of Respiratory Syncytial Virus Lower Respiratory Tract Disease (RSV-LRTD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-01
Completion: 2025-06-03
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL COMBINATION_PRODUCT
No Results Yet
NCT06613724 | COMPLETED | NA
10 Participants

Magnetic Duodeno-Ileal Chile Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-14
Completion: 2025-02-27
Conditions
Obesity Type 2 Diabetes Mellitus (T2DM)
Interventions
DEVICE
No Results Yet
NCT06607003 | RECRUITING | PHASE1
200 Participants

Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-26
Completion: 2026-07-15
Conditions
Malaria
Interventions
BIOLOGICAL
No Results Yet
NCT06592378 | RECRUITING | NA
100 Participants

Opioid Management for Discharged Emergency Department Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-27
Completion: 2026-05-31
Conditions
Bone Fractures
Interventions
DEVICE
No Results Yet
NCT06575192 | RECRUITING | PHASE3
783 Participants

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-05
Completion: 2029-12-31
Conditions
Breast Reconstruction
Interventions
DEVICE OTHER
No Results Yet
NCT06573294 | RECRUITING | PHASE1
45 Participants

Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-08-28
Completion: 2026-11-01
Conditions
Advanced Malignant Solid Tumors Metastatic Malignant Solid Tumors
Interventions
DRUG
No Results Yet
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