Clinical Trials
Showing trials with last updates posted in 2025.
20
Participants
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-10-12
Completion:
2026-10-31
Conditions
Extracorporeal Membrane Oxygenation Complication
Neonatal Aspiration Pneumonia
Acute Respiratory Failure
Acute Lung Injury
Interventions
DEVICE
No Results Yet
144
Participants
PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-13
Completion:
2026-12-31
Conditions
Alzheimer Disease, Early Onset
Interventions
DRUG
No Results Yet
300
Participants
A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-18
Completion:
2028-06-30
Conditions
Lower Extremity Acute Limb Ischemia
LE ALI
Interventions
DEVICE
No Results Yet
200
Participants
Trial of Orbital Atherectomy Versus Standard Strategy in Calcified Bifurcation Lesions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-10-23
Completion:
2025-12-31
Conditions
Coronary Artery Disease
Coronary Disease
Interventions
DEVICE
No Results Yet
45
Participants
Patient-identified Values as Outcome Targets (PIVOT) Feasibility Pilot Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-18
Completion:
2027-08-31
Conditions
Peripheral Neuropathy Due to Chemotherapy
Interventions
BEHAVIORAL
No Results Yet
407
Participants
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-03
Completion:
2027-04-30
Conditions
Persistent Atrial Fibrillation
Interventions
DEVICE
No Results Yet
15
Participants
Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-10
Completion:
2026-03-01
Conditions
Autoimmune Lymphoproliferative Syndrome
Interventions
DRUG
No Results Yet
100
Participants
Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-18
Completion:
2026-08-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
12
Participants
Cell Therapy for Corneal Endothelial Cell Dysfunction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-25
Completion:
2028-12-31
Conditions
Corneal Endothelial Cell Dysfunction
Interventions
DRUG
No Results Yet
33
Participants
Futibatinib in Combination With (Chemo)Immunotherapy in Colorectal Cancer and Other Solid Tumor Entities
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-16
Completion:
2028-03-31
Conditions
Colorectal Cancer
Interventions
DRUG
No Results Yet
202
Participants
A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-01-06
Completion:
2026-10-16
Conditions
Macular Degeneration, Age-related
Geographic Atrophy
Interventions
DRUG
No Results Yet
350
Participants
A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-16
Completion:
2026-12-31
Conditions
Alzheimer Disease
Dementia
Interventions
DRUG
No Results Yet
1046
Participants
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-01-27
Completion:
2029-07-02
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
45
Participants
Study to Evaluate the Efficacy and Safety of VGR-R01 Gene Therapy in Patients With Bietti Crystalline Dystrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-13
Completion:
2026-12-01
Conditions
Bietti Crystalline Dystrophy
Inherited Retinal Diseases
Interventions
DRUG
No Results Yet
110
Participants
A Study to Assess the Safety, Tolerability, and Interactions of ABBV-CLS-616 Oral Tablets in Healthy Adult Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-11
Completion:
2026-01-08
Conditions
Healthy Volunteer
Interventions
DRUG
No Results Yet
167
Participants
Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Attacks In Canada
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-12
Completion:
2026-01-31
Conditions
Migraine
No Results Yet
880
Participants
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-18
Completion:
2029-02-05
Conditions
Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
60
Participants
The RECAP2 Study: Midazolam and Psilocybin
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-08-07
Completion:
2027-12-31
Conditions
Psilocybin
Interventions
DRUG
No Results Yet
81
Participants
Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-26
Completion:
2030-04-18
Conditions
Breast Neoplasms
Breast Cancer
Interventions
BIOLOGICAL
No Results Yet
120
Participants
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-03
Completion:
2026-12-01
Conditions
Antibody-mediated Rejection
Interventions
DRUG
No Results Yet
50
Participants
The Role of Focus Strategies on Pilates
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-05
Completion:
2025-04-15
Conditions
Reaction Time
Humans
Exercise Therapy
Exercise Movement Techniques
Pilates
Interventions
OTHER
No Results Yet
110
Participants
A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-28
Completion:
2028-03-31
Conditions
Advanced High-Grade Epithelial Ovarian
Primary Peritoneal
Fallopian Tube Cancers
High Folate Receptor-Alpha Expression
Platinum Resistant
Interventions
DRUG
No Results Yet
1112
Participants
Intention to Change and Treatment-Seeking in Pathological Gamblers and Investors: An Experimental Study in Young Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-20
Completion:
2025-06-30
Conditions
Gambling Disorder
Interventions
BEHAVIORAL
No Results Yet
15
Participants
CD19 CAR-T in the Treatment of Relapsed/Refractory Autoimmune Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-15
Completion:
2027-12-31
Conditions
Autoimmune Diseases
Interventions
DRUG
No Results Yet
700
Participants
ELEVATE-HFpEF Clinical Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-09
Completion:
2028-08-31
Conditions
Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions
DEVICE
No Results Yet
3082
Participants
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-02
Completion:
2031-01-26
Conditions
Coronavirus Disease (COVID-19)
Interventions
DRUG
No Results Yet
2067
Participants
The Ohio State University (OSU) SCREEN Community Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-12
Completion:
2029-12-31
Conditions
Breast Carcinoma
Cervical Carcinoma
Colorectal Carcinoma
Interventions
OTHER
BEHAVIORAL
PROCEDURE
No Results Yet
170
Participants
A Study of JNJ-89402638 for Metastatic Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-15
Completion:
2028-02-25
Conditions
Unresectable Metastatic Colorectal Cancer
Interventions
DRUG
No Results Yet
19
Participants
A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-22
Completion:
2026-01-19
Conditions
Lymphoma, Non-Hodgkin
Interventions
DRUG
No Results Yet
850
Participants
Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-02
Completion:
2026-12-01
Conditions
Stroke, Ischemic
Stroke, Acute
Thrombosis, Brain
Drug Effect
Interventions
DRUG
No Results Yet
280
Participants
WATER IV Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-03
Completion:
2027-07-31
Conditions
Localized Prostate Cancer
Interventions
DEVICE
PROCEDURE
No Results Yet
150
Participants
Dynamic ctDNA Assessment in Cervical and Anal Canal Tumors: Optimizing Follow-up and Clinical Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-14
Completion:
2026-12-31
Conditions
HPV-Related Carcinoma
Uterine Cervical Cancer
Anal Canal Cancer
HPV-Related Anal Squamous Cell Carcinoma
HPV-Related Cervical Carcinoma
Interventions
DIAGNOSTIC_TEST
DRUG
No Results Yet
9
Participants
Dose Escalation of Allogeneic Adipose Derived Stroma/Stem Cells for the Treatment of Crohn's Fistula
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-12
Completion:
2027-09-30
Conditions
Crohn Disease
Interventions
DRUG
No Results Yet
0
Participants
STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-05
Completion:
2027-10-30
Conditions
Locally Advanced Cervical Carcinoma
Locally Advanced Colorectal Carcinoma
Locally Advanced Malignant Solid Neoplasm
Locally Advanced Melanoma
Locally Advanced Pancreatic Ductal Adenocarcinoma
Locally Advanced Renal Cell Carcinoma
Metastatic Cervical Carcinoma
Metastatic Colorectal Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Melanoma
Metastatic Pancreatic Ductal Adenocarcinoma
Metastatic Renal Cell Carcinoma
Stage II Pancreatic Cancer AJCC v8
Stage III Cervical Cancer AJCC v8
Stage III Colorectal Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Stage III Renal Cell Cancer AJCC v8
Stage IV Cervical Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
Unresectable Cervical Carcinoma
Unresectable Colorectal Carcinoma
Unresectable Malignant Solid Neoplasm
Unresectable Melanoma
Unresectable Pancreatic Ductal Adenocarcinoma
Unresectable Renal Cell Carcinoma
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
680
Participants
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-21
Completion:
2033-05-16
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
DRUG
OTHER
No Results Yet
416
Participants
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-04
Completion:
2031-02-26
Conditions
Lung Cancer
Breast Cancer
Interventions
DRUG
No Results Yet
24
Participants
Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-31
Completion:
2026-12-31
Conditions
Metastatic Lung Non-Small Cell Carcinoma
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
0
Participants
Effect of Capivasertib on ctDNA in ER Positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-01
Completion:
2025-09-16
Conditions
Breast Cancer
Oestrogen Receptor Positive Breast Cancer
Interventions
DRUG
No Results Yet
20
Participants
Development of Tumor Organoids From Undifferentiated Primary Carcinomas to Guide Therapeutic Decisions
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-05
Completion:
2028-12-15
Conditions
Undifferentiated Carcinoma
Interventions
OTHER
No Results Yet
600
Participants
Effects of E-cigarette Use on Health
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-01-06
Completion:
2029-06-30
Conditions
Electronic Cigarette Use
Interventions
OTHER
No Results Yet
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