Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Attacks In Canada

NCT ID: NCT06692881

Last Updated: 2025-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

167 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-12

Study Completion Date

2026-01-31

Brief Summary

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Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate function and satisfaction with oral ubrogepant in treating adult participants after multiple migraine attacks.

Ubrogepant is a drug approved for the acute treatment of migraine in adults. Approximately 167 participants will be enrolled in approximately 10-15 sites across Canada.

Participants will receive ubrogepant as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 12 weeks.

There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Detailed Description

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Conditions

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Migraine

Keywords

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Migraine ubrogepant Ubrelvy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ubrogepant

Participants will receive Ubrogepant as prescribed by their physician in routine clinical practice.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Participants able to give voluntary informed consent before starting any study-related assessments or procedures (to be obtained/documented as per local regulations).
* Adults (≥18 years of age) at time of informed consent.
* Participants with at least 1-year history of migraine with or without aura consistent with a diagnosis according to the ICHD-3 (2018).
* Participants with history of experiencing at least 3 migraine attacks per month with moderate to severe symptoms
* Participants prescribed ubrogepant by investigator for the acute treatment of migraine according to local product label, independent of and prior to study participation
* Participants willing and able to comply with the requirements of the study.
* Participants with access to an electronic device (mobile phone, tablet, laptop, etc.) with internet access.

Exclusion Criteria

* Participants previously exposed to a ubrogepant or rimegepant as routine therapy or through a clinical trial.
* Participants with history of known contraindications to ubrogepant as per local labeling.
* Participants Pregnant or planning to be pregnant or of childbearing potential not using contraception
* Participants enrolled in any interventional studies that may include investigational compounds for migraine or non-AbbVie observational studies.
* History or current evidence of any condition that might interfere with their ability to comply with the study requirements, in the opinion of the investigator.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AbbVie

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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ABBVIE INC.

Role: STUDY_DIRECTOR

AbbVie

Locations

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Calgary Headache Assessment and Management Program /ID# 271475

Calgary, Alberta, Canada

Site Status RECRUITING

Burrard Health Center /ID# 271474

Vancouver, British Columbia, Canada

Site Status RECRUITING

Royal Jubilee Hospital /ID# 271476

Victoria, British Columbia, Canada

Site Status RECRUITING

Maritime Neurology /ID# 271867

Halifax, Nova Scotia, Canada

Site Status RECRUITING

Neurocentre of Eastern Ontario /ID# 271865

Kingston, Ontario, Canada

Site Status RECRUITING

Centricity /ID# 271477

London, Ontario, Canada

Site Status RECRUITING

London Health Sciences Centre - Victoria Hospital & Children's Hospital /ID# 272031

London, Ontario, Canada

Site Status RECRUITING

360 Concussion Care /ID# 271972

Ottawa, Ontario, Canada

Site Status RECRUITING

Bayshore Neurology /ID# 280213

Ottawa, Ontario, Canada

Site Status RECRUITING

Sunnybrook Health Sciences Centre /ID# 276844

Toronto, Ontario, Canada

Site Status RECRUITING

Centre de Recherche St-Louis /ID# 272843

Lévis, Quebec, Canada

Site Status RECRUITING

Genge Partners /ID# 273302

Montreal, Quebec, Canada

Site Status RECRUITING

Diex Recherche Sherbrooke /ID# 271677

Sherbrooke, Quebec, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Kelly Boyd

Role: CONTACT

Phone: 5148327258

Email: [email protected]

Related Links

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Other Identifiers

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P25-245

Identifier Type: -

Identifier Source: org_study_id